Mid-term Results of Epiphyseal Transfer for Hip Post Septic Epiphyseal Loss

NCT ID: NCT07321418

Last Updated: 2026-01-07

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 20 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-12-25
• Study Completion Date: 2028-12-30

Brief Summary

Absence or loss of the growth plate together with the epiphysis of a long bone presents a very difficult condition to treat. An example of this is the loss of the head and neck of the femur especially as a part of severe sequelae of infantile septic arthritis.

Detailed Description

Ever since its advent by Taylor in 1975 , the vascularized fibular free flap has gained popularity and became the gold standard to reconstruct challenging bony defects of the head, neck and extremities. Vascularized fibular flaps offer a great deal of versatility, particularly when reconstructing bony defects larger than 6 cm. In skeletally immature patients, vascularized epiphyseal transfer allows for reconstruction of complex bony defects preserving ongoing longitudinal growth, and provides a reliable articular surface for effective joint function. Although the proximal fibular growth plate is the most popular type of transfer. Therefore, it's mandatory to assess follow up of patients underwent epiphyseal transfer.

Earlier reports of proximal fibular epiphyseal transfer described the use of the peroneal vessels as the pedicle, However the results were overall disappointing and the peroneal artery alone was concluded to be insufficient to support the physeal growth plate. A bipedicled transfer, using the peroneal vessels to support the diaphysis and the anterior tibial vessels or the inferior lateral genicular vessels to support the epiphysis was attempted. Although this showed better outcomes, it was technically more demanding and had a higher risk of complications. Taylor reported the use of the anterior tibial vessels as a single pedicle with success after confirming its role in the blood supply of the fibular diaphysis and epiphysis in a cadaveric study. Another study further popularized the use of the anterior tibial pedicle after introducing the "reverse flow" method and describing the harvest technique. A reported drawback for the use of the anterior tibial pedicle was the occasional need to transect branches of the deep peroneal nerve during the harvest due to their complex relation to the vessels.

This variability in the vascular pedicle employed mandated to the need for a detailed anatomical study of the blood supply of the proximal fibula including the head region, and the supplying vessels, in order to give surgeons appropriate information for choosing the ideal vessel for these complex cases and minimize donor site morbidity. To the best of our knowledge, no such study has been conducted or published in the literature. Moreover, no study has described the anatomic relationship of the deep peroneal nerve branches to the tibialis anterior muscle and their relation to the supplying vessels, which represents another obstacle in the face of popularizing this highly beneficial technique.

Absence or loss of the growth plate together with the epiphysis of a long bone presents a very difficult condition to treat. An example of this is the loss of the head and neck of the femur especially as a part of severe sequelae of infantile septic arthritis. Another example is congenital radial longitudinal deficiency with a previously failed centralization procedure. Management strategies of these and similar problematic conditions are limited and unsatisfactory, with major residual functional disability. Vascularized epiphyseal transfer presents a potential solution to such problems.

Conditions

Septic Arthritis of the Native Hip; Epiphyseal Arrest, Lower Leg

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: RETROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• All cases in Hand and Reconstructive Microsurgery Unit in AUH with epiphyseal transfer for hip post-septic epiphyseal loss.
• Minimum 5 years Follow-up records .

Exclusion Criteria

• Uncontrolled local infection .
• Patients with incomplete data.

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Mostafa Ahmed Mostafa Abdelbaky

Resident

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

Mostafa

Identifier Type: -

Identifier Source: org_study_id