Sequelae of Developmental Dysplasia of the Hip

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

340 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-31

Study Completion Date

2026-12-31

Brief Summary

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The aim of this study is to assess long term effects of developmental dysplasia of the hip (DDH) to overall health and quality of life later in life. We compare hip radiographs, hip symptoms, clinical examination, head asymmetry, dental examination and intraoral scans of 170 children and young adults treated for DDH in their childhood with age and sex matched controls.

Detailed Description

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Developmental dysplasia of the hip (DDH) is the most common musculoskeletal disorder in infancy. However there are few reports of long term effects of successfully treated DDH. Incidence of DDH in neonatal period is approximately 1-10/1000 depending on screening protocols used, the age of the infant during screening and which ultrasonographic findings are considered normal and which DDH. The prevalence of hip dysplasia in adult population is grossly 4 % when using Wibergs Centre-Edge (CE) ≤ 20° as definition of dysplasia. It is still unclear, what is the relation between adult acetabular dysplasia and developmental dysplasia in children. Hip dysplasia overall is a major contributing factor in hip osteoarthrosis and total hip replacement in young adults.

The aim of this study is to assess long term effects of developmental dysplasia of the hip to overall health and quality of life later in life. We compare hip radiographs, hip symptoms, clinical examination, head asymmetry, dental examination and intraoral scans of 170 children and young adults treated for DDH in their early childhood with age and sex matched controls.

Conditions

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Developmental Dysplasia of the Hip Hip Dysplasia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Treated for DDH in childhood

Subjects have had DDH in childhood. DDH has been diagnosed before age of 1,5 years and treated for.

No interventions assigned to this group

Control

Age an sex matched controls of DDH patients

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* DDH has been diagnosed by clinical examination, ultrasound examination or by radiological examination and treatment begun before age of 1,5 years.
* Treated in Oulu University Hospital

Exclusion Criteria

* neurological or developmental condition which can influence hip development such as cerebral palsy or spina bifida
* other significant congenital anomalies of musculoskeletal system such as club feet

Minimum Eligible Age

10 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Juhana Leppilahti, Professor

Role: PRINCIPAL_INVESTIGATOR

University of Oulu

Marita Valkama, Ph.D., M.D

Role: STUDY_DIRECTOR

University of Oulu, Oulu University Hospital, MRC Oulu

Virpi Harila, Ph.D.

Role: STUDY_DIRECTOR

University of Oulu, MRC Oulu

Locations

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University of Oulu; Oulu University Hospital

Oulu, , Finland

Site Status

Countries

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Finland

Other Identifiers

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EETTMK:94/2014

Identifier Type: -

Identifier Source: org_study_id