Quality of Life, Psychological Impact, and Care-related Challenges in Patients Affected by Von Hippel-Lindau Syndrome.

NCT ID: NCT07275099

Last Updated: 2026-01-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2026-02-01

Study Completion Date

2035-12-01

Brief Summary

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This is a single-centre, cross-sectional observational study aiming to assess the psychological burden, quality of life, and perceived barriers to care in patients with von Hippel-Lindau syndrome (VHL). Data will be collected through an anonymous online questionnaire, specifically designed for the study and administered via Google Forms.

Detailed Description

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This is a single-centre, cross-sectional observational study designed to assess the psychological burden and health-related quality of life in individuals with von Hippel-Lindau (VHL) syndrome, and to explore perceived barriers to healthcare access and the perceived adequacy of multidisciplinary care.

The hypothesis underlying this study is that individuals affected by VHL experience a substantial psychological burden and face variable access to appropriate care pathways, which may differ based on demographic or clinical factors.

The study will involve a single group of participants (n ≈ 200). No control group or randomization is foreseen. The study duration is estimated at 10 years, including data collection and analysis.

Each participant will be involved once, with a single data collection session (approx. 25-30 minutes) through the study-specific questionnaire "VHL: Accesso alle cure e vita quotidiana". The questionnaire, administered in Italian via the Google Forms platform, is not part of routine clinical practice and is administered exclusively for research purposes.

Conditions

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VHL - Von Hippel-Lindau Syndrome

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Single - centre, cross - sectional observational study with additional procedure.

Adult subjects (≥ 18 years) with confirmed diagnosis of von Hippel - Lindau syndrome

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age ≥18 years
* Genetically confirmed diagnosis of von Hippel- Lindau syndrome

Exclusion Criteria

* Inability to understand or complete the questionnaire, either independently or with assistance
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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IRCCS Ospedale San Raffaele

OTHER

Sponsor Role lead

Responsible Party

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Larcher Alessandro

Medical Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Alessandro Larcher

Role: CONTACT

+39 02.2643.4121

Other Identifiers

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QoL- VHL

Identifier Type: -

Identifier Source: org_study_id

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