Moisturization and Skin Hydration Study

NCT ID: NCT07270965

Last Updated: 2025-12-08

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 30 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-12-31
• Study Completion Date: 2026-12-31

Brief Summary

Skin moisturization is important for patients with atopic dermatitis, commonly known as eczema. Moisturizing right after bathing is widely accepted as the best method to keep skin hydrated. However, there is conflicting research on the timing of moisturizing. The goal of this clinical study is to evaluate the preference of moisturizing while showering/bathing compared to after towel drying in adolescents aged 12-18 with eczema. The main question it aims to answer are:

• Which moisturization technique is preferred: while showering/bathing or after towel drying?
• How do these techniques affect investigator-assessed eczema severity, patient-reported itch scores, and objective skin hydration measurements?

Researchers will compare applying moisturizer while in the shower/bath to after towel drying and to which technique is preferred among participants and if there are different effects on eczema and skin hydration.

Participants will:

• Apply moisturizer while showering/bathing for one month and after towel drying for one month.
• Complete questionnaires on moisturization technique, skin feel, and itchiness.
• Undergo skin hydration measurements using a Corneometer® CM825 device.

Conditions

Atopic Dermatitis (AD); Atopic Dermatitis (Eczema)

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: PREVENTION
• Blinding Strategy: NONE

Study Groups

Moisturizing while in shower/bath

Group Type: EXPERIMENTAL

Moisturizing while in shower/bath

Intervention Type: BEHAVIORAL

Applying moisturizer in the shower/bath.

Moisturizing after towel drying

Group Type: EXPERIMENTAL

Moisturizing after towel drying

Intervention Type: BEHAVIORAL

Applying moisturizer out of the shower/bath after towel drying.

Interventions

Moisturizing while in shower/bath

Applying moisturizer in the shower/bath.

Intervention Type: BEHAVIORAL

Moisturizing after towel drying

Applying moisturizer out of the shower/bath after towel drying.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Participants must have a diagnosis of atopic dermatitis/eczema.
• Participants must be between the age of 12-18.
• Participants must be able to bathe independently.
• Participants will be English speaking and able to complete questionnaires.

Exclusion Criteria

• Participants who use topical corticosteroids between one inch above the wrist and 1 inch below the elbow from 1 month on both arms prior to the study until the final visit.
• Participants who have a known allergy to the moisturizer cream (Cerave Moisturizing Cream) provided.

• Minimum Eligible Age: 12 Years
• Maximum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

L'Oreal

INDUSTRY

Sponsor Role: collaborator

University of British Columbia

OTHER

Sponsor Role: lead

Responsible Party

Wingfield Rehmus

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

BC Children's Hospital

Vancouver, British Columbia, Canada

Countries

Canada

Central Contacts

Wingfield Rehmus, MD, MPH

Role: CONTACT

dermatologyresearch@cw.bc.ca

1-604-875-2606

Other Identifiers

H25-02646

Identifier Type: -

Identifier Source: org_study_id