Intravenous Atropine in Reducing Reperfusion Arrhythmias, Conduction Abnormalities and Hypotension in Inferior ST-elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
NCT ID: NCT07268586
Last Updated: 2025-12-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
PHASE4
150 participants
INTERVENTIONAL
2025-08-01
2025-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
TRIPLE
Study Groups
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Atropine arm
This group will receive intravenous atropine 1 mg immediately before wire crossing
Intravenous atropine immediately before wire crossing during primary percutaneous coronary intervention
Intravenous atropine 1 mg immediately before wire crossing during primary percutaneous coronary intervention
Placebo arm
This group will receive intravenous normal saline immediately before wire crossing
Intravenous normal saline as placebo immediately before wire crossing during primary percutaneous coronary intervention
Intravenous normal saline as placebo immediately before wire crossing during primary percutaneous coronary intervention
Interventions
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Intravenous atropine immediately before wire crossing during primary percutaneous coronary intervention
Intravenous atropine 1 mg immediately before wire crossing during primary percutaneous coronary intervention
Intravenous normal saline as placebo immediately before wire crossing during primary percutaneous coronary intervention
Intravenous normal saline as placebo immediately before wire crossing during primary percutaneous coronary intervention
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Mechanical complications or no reflow or spontaneous reperfusion.
* Prior implantation of permanent or temporary pacemakers
* History of bradycardia, hypotension or ventricular tachycardia with a definitive cause (unrelated to the disease under study)
* Prior coronary artery bypass graft surgery
* Atropine contraindications Unwillingness to participate in the
18 Years
ALL
No
Sponsors
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Ain Shams University
OTHER
Responsible Party
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Locations
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Ain Shams University
Cairo, Abbasia, Egypt
Countries
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Central Contacts
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Other Identifiers
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FMASU R49/2025
Identifier Type: -
Identifier Source: org_study_id
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