Additional Effects Of Brandt-Daroff Exercises With GANS Maneuver On Dizziness And Quality Of Life In Patients With BPPV

NCT ID: NCT07267988

Last Updated: 2025-12-05

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 30 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-09-13
• Study Completion Date: 2026-01-10

Brief Summary

Benign Paroxysmal Positional Vertigo (BPPV) is the most common cause of recurrent vertigo, with a lifetime prevalence of about 2.4% and a yearly incidence of roughly 0.6%. It results from displaced otoconia within the semicircular canals and is especially common in older adults. BPPV leads to brief, position-provoked episodes of vertigo, dizziness, and imbalance, and reduced quality of life. Although canalith-repositioning maneuvers are highly effective, recurrence is common, emphasizing the need for supportive and adjunctive management strategies.This randomized controlled trial will evaluate the Additional Effects OF Brandt-Daroff Exercise With GANS Maneuver On dizziness And Quality of Life In Patients with BPPV. Thirty patients with BPPV will be recruited at Fauji Foundation Hospital and screened using the Dizziness Handicap Inverntory Scale(DHI) and Vestibular Activities and Participation measure(VAP). Participants will be randomized into two groups: (1) Reciving GANS Manuever Alone (2) GANS Manuever with Brandt-Daroff Exercises(3 sessions per week/40minutes). Dizziness will be assessed using the Dizziness Handicap Inverntory Scale(DHI) , quality of life using the Activities and Participation Measure(VAP) Scale. Outcome measures will be recorded at baseline and post-intervention. Ethical approval will be obtained from FUMC ERC, and data will be analyzed using SPSS v.22.

Detailed Description

Benign Paroxysmal Positional Vertigo (BPPV) is a common and disabling vestibular disorder, affecting approximately 2.4% of individuals during their lifetime and accounting for nearly 20-30% of vertigo cases in clinical settings. It is caused by the displacement of otoconia into the semicircular canals, leading to brief episodes of vertigo and dizziness, that significantly disrupt daily activities and reduce quality of life. The high prevalence of BPPV is associated with increased risks of falls, functional limitations, and recurrent episodes. Although canalith repositioning maneuvers serve as the primary treatment, recurrence rates remain substantial, underscoring the need for adjunctive therapeutic approaches that address persistent vertigo and improve overall functional outcomes.This study aims to investigate the additional effects GANS maneuver and Brandt-Daroff exercise on dizziness reduction, and quality of life improvement, in BPPV Patients .A randomized controlled trial will be conducted with participants diagnosed with BPPV.This study will be a non blinded, randomized controlled trial with two groups: the intervention group, which will receive GANS Maneuver with Brandt-Daroff Exercises, and the control group, which will receive GANS Maneuver alone. The intervention will last for six weeks, with participants attending two 40-minute sessions per week. A total of 30 individuals with BPPV will be recruited and randomly assigned to one of the two groups. The Dizziness Handicap Inventory Scale(DHI) will be used to screen for dizziness. Quality of life will be measured using the Vestibular and Participation Scale(VAP).The study will be conducted over a period of 1 year at Fauji Foundation Hospital. Ethical approval will be obtained from FUMC ERC. Recruited participants will be allocated to either group through a random sampling method. Outcome measurements will be taken at baseline and again after the 6-week intervention period. Individuals meeting the inclusion criteria will be selected, and written informed consent will be obtained after explaining the study's purpose. Data will be entered and analyzed on SPSS v. 22.

Conditions

BPPV; Dizziness; Quality of Life

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

GANS Maneuver with Brand-Daroff Exercises

GANS Maneuver include:

1. Sit upright on a bed with legs extended.

2. Turn patient head 45° toward the affected ear.

3. Quickly lie back so patient head is slightly hanging over the edge

4. Hold this position 30-60 seconds or until vertigo stops.

5. Without lifting the head, rotate it 90° toward the opposite side (45° past midline).

6. Hold again for 30-60 seconds.

7. Continue turning patient head in the same direction and roll onto side so nose faces the floor.

8. Hold 30-60 seconds.

9. Sit up slowly, keeping patient chin slightly tucked.

10. Rest in sitting for about a minute. (3 reps/2 times per week) BRANDTDAROFF EXERCISES Sit upright on the edge of your bed. Turn your head 45° to the left. Keeping the head turned, quickly lie down on your right side. Hold this position 30 seconds or until vertigo stops. Return to sitting; hold 30 seconds. Turn your head 45° to the right. Quickly lie down on your left side. Hold 30 seconds or until vertigo stops. Return to sitting; hold 30 seconds.

Group Type: EXPERIMENTAL

GANS Maneuver with Brandt-Daroff Exercises

Intervention Type: PROCEDURE

The intervention program spans six weeks and involves both supervised Gans Maneuver sessions and home-based Brandt-Daroff exercises. Participants will attend two supervised Gans sessions per week, with each session consisting of three repetitions of the maneuver.

In addition, participants will perform Brandt-Daroff exercises at home twice daily, with each cycle consisting of three repetitions. This combination of supervised and home-based practice will be maintained consistently throughout all six weeks. Across the entire program, participants will complete a total of 12 supervised Gans sessions and 36 Brandt-Daroff home sessions.

GANS Maneuver

GANS Maneuver include:

1. Sit upright on a bed with legs extended.

2. Turn patient head 45° toward the affected ear.

3. Quickly lie back so patient head is slightly hanging over the edge

4. Hold this position 30-60 seconds or until vertigo stops.

5. Without lifting the head, rotate it 90° toward the opposite side (45° past midline).

6. Hold again for 30-60 seconds.

7. Continue turning patient head in the same direction and roll onto side so nose faces the floor.

8. Hold 30-60 seconds.

9. Sit up slowly, keeping patient chin slightly tucked.

10. Rest in sitting for about a minute. (3 reps/2 times per week)

Group Type: ACTIVE_COMPARATOR

Gans Maneuver

Intervention Type: PROCEDURE

The control group will participate in a structured six-week intervention program consisting exclusively of the Gans Maneuver. Participants will attend two supervised sessions per week, ensuring consistent oversight and proper technique throughout the program. Each session will include three repetitions of the maneuver, with participants allowed a rest period of 30 to 60 seconds between repetitions to prevent fatigue and maintain the quality of each movement. This frequency and volume are maintained consistently across all six weeks to provide a standardized exposure, allowing for accurate comparison with other intervention groups. Over the entire six-week period, participants will complete a total of 12 supervised sessions, each with three repetitions, summing up to 36 repetitions across the intervention.

Interventions

GANS Maneuver with Brandt-Daroff Exercises

The intervention program spans six weeks and involves both supervised Gans Maneuver sessions and home-based Brandt-Daroff exercises. Participants will attend two supervised Gans sessions per week, with each session consisting of three repetitions of the maneuver.

In addition, participants will perform Brandt-Daroff exercises at home twice daily, with each cycle consisting of three repetitions. This combination of supervised and home-based practice will be maintained consistently throughout all six weeks. Across the entire program, participants will complete a total of 12 supervised Gans sessions and 36 Brandt-Daroff home sessions.

Intervention Type: PROCEDURE

Gans Maneuver

The control group will participate in a structured six-week intervention program consisting exclusively of the Gans Maneuver. Participants will attend two supervised sessions per week, ensuring consistent oversight and proper technique throughout the program. Each session will include three repetitions of the maneuver, with participants allowed a rest period of 30 to 60 seconds between repetitions to prevent fatigue and maintain the quality of each movement. This frequency and volume are maintained consistently across all six weeks to provide a standardized exposure, allowing for accurate comparison with other intervention groups. Over the entire six-week period, participants will complete a total of 12 supervised sessions, each with three repetitions, summing up to 36 repetitions across the intervention.

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Diagnosed Patients of Benign Paroxysmal Vertigo (BPPV)
• Age between 18-60
• Acute and Chronic BPPV Patients
• Positive Dix-Hallpike Test
• DHI Scale: Mild-Severe (0-100)

Exclusion Criteria

• Patients with a history of vestibular surgery or cochlear
• Patients with a history of seizures or epilepsy
• Patients with a pacemaker or implantable cardioverter-defibrillator (ICD)
• Patients with a history of severe head injury or concussion within the past year
• No other vestibular disorders or conditions that may affect balance (e.g., Meniere's disease, labyrinthitis
• No musculoskeletal or neurological conditions that may affect balance (e.g., stroke, Parkinson's disease)

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Foundation University Islamabad

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Foundation University College of Physical Therapy

Islamabad, , Pakistan

Site Status: RECRUITING

Countries

Pakistan

Central Contacts

Rabia Ejaz, DPT

Role: CONTACT

rabiaejaz57@gmail.com

+92 3145281989

Facility Contacts

Furqan Ahmed Siddiqi, Phd

Role: primary

principal.fucp@fui.edu.pk

051 5788582 ext. 602

Other Identifiers

FUI/CTR/2025/12

Identifier Type: -

Identifier Source: org_study_id