Treatments for Benign Paroxysmal Positional Vertigo (BPPV)
NCT ID: NCT00000359
Last Updated: 2012-07-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
PHASE2
150 participants
INTERVENTIONAL
1998-10-31
2003-06-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Keywords
Explore important study keywords that can help with search, categorization, and topic discovery.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
TREATMENT
SINGLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Canalith repositioning maneuver
Repositioning treatment for posterior canal BPPV
Canalith repositioning maneuver (Epley maneuver)
Standard passive motion of the head: Dix-Hallpike maneuver, turn head to opposite side, roll over, sit up.
Modified Epley maneuver
Vestibular habituation exercises
Head shaking exercises in pitch, roll, yaw and circumduction. Titrating from 2 repetitions per exercise to 20 repetitions per exercise, as tolerated.
Sham
The subject sat in a chair; the head was passively tilted downward, turned away from the involved side, turned back to center, upward, away from the involved side, twice, slowly.
ShamManeuver
Passive movement of the head
Liberatory maneuver
The standard liberatory maneuver (also known as the Semont maneuver) was used.
Semont maneuver
Sidelying maneuver, flip over 180 deg, sit up.
Brandt Daroff exercise
Modified Brandt Daroff exercise performed as a self-liberatory exercise.
Brandt-Daroff exercises
Active exercise. Sidelying to involved side, sidelying to uninvolved side, sit up.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Canalith repositioning maneuver (Epley maneuver)
Standard passive motion of the head: Dix-Hallpike maneuver, turn head to opposite side, roll over, sit up.
Semont maneuver
Sidelying maneuver, flip over 180 deg, sit up.
Brandt-Daroff exercises
Active exercise. Sidelying to involved side, sidelying to uninvolved side, sit up.
Vestibular habituation exercises
Head shaking exercises in pitch, roll, yaw and circumduction. Titrating from 2 repetitions per exercise to 20 repetitions per exercise, as tolerated.
ShamManeuver
Passive movement of the head
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Are at least 21 years old.
* Have a diagnosis of unilateral posterior semicircular canal BPPV according to established clinical test criteria.
* Have functional to normal range of motion of the neck and the back.
Exclusion Criteria
* Have a history of prior ear surgery or prior treatment for BPPV.
* Have an orthopedic or connective tissue disorder that impairs functional neck or trunk range of motion.
* Have a significant neurological disorder or spinal cord damage.
* Are on vestibular suppressant medications.
* Have Meniere's disease or acoustic neuromas.
21 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Baylor College of Medicine
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Helen Cohen
Professor
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Helen Cohen, EdD
Role: PRINCIPAL_INVESTIGATOR
Baylor College of Medicine
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Baylor College of Medicine
Houston, Texas, United States
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Cohen HS. Side-lying as an alternative to the Dix-Hallpike test of the posterior canal. Otol Neurotol. 2004 Mar;25(2):130-4. doi: 10.1097/00129492-200403000-00008.
Cohen HS, Kimball KT, Stewart MG. Benign paroxysmal positional vertigo and comorbid conditions. ORL J Otorhinolaryngol Relat Spec. 2004;66(1):11-5. doi: 10.1159/000077227.
Cohen HS, Kimball KT. Treatment variations on the Epley maneuver for benign paroxysmal positional vertigo. Am J Otolaryngol. 2004 Jan-Feb;25(1):33-7. doi: 10.1016/j.amjoto.2003.09.010.
Cohen HS, Kimball KT. Effectiveness of treatments for benign paroxysmal positional vertigo of the posterior canal. Otol Neurotol. 2005 Sep;26(5):1034-40. doi: 10.1097/01.mao.0000185044.31276.59.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.