Carotid Doppler Screening for Subclinical Atherosclerosis in Diabetic CKD Patients.

NCT ID: NCT07266220

Last Updated: 2025-12-05

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 96 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2026-01-31
• Study Completion Date: 2027-04-30

Brief Summary

This study is being done at Assiut University to look for early signs of hardening of the arteries (atherosclerosis) in people who have both diabetes and chronic kidney disease (CKD). Many patients with these conditions are at higher risk of heart disease and stroke, but the disease can develop quietly without symptoms.

We will use a safe, non-invasive test called carotid Doppler ultrasound, which uses sound waves to check the neck arteries (carotid arteries) for early changes. The goal is to see how often these early changes occur in patients with diabetes and CKD, and whether the findings relate to their kidney function, blood sugar control, and other health factors.

This research may help doctors detect vascular problems earlier and guide better prevention strategies for patients at risk.

Conditions

Diabetes Mellitus, Type 2; Chronic Kidney Disease; Atherosclerosis

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Eligibility Criteria

Inclusion Criteria

1. Age≥18years.

2. Diagnosis of type 2 diabetes mellitus (per treating physician or ADA criteria).

3. CKDstage3:eGFR30-59mL/min/1.73 m² on at least two measurements ≥3 months apart OR established diagnosis in medical record.

4. Clinically stable (no AKI, no hospitalization for cardiovascular event in past 3 months).

5. Ableandwilling to provide informed consent.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Abdallah Ali Mohammed

OTHER

Sponsor Role: lead

Responsible Party

Abdallah Ali Mohammed

Resident Physician, Internal Medicine

Responsibility Role: SPONSOR_INVESTIGATOR

Other Identifiers

AUN-IM-CKD-CAROTID-2025

Identifier Type: -

Identifier Source: org_study_id