Matrix Metalloproteinases in Atherosclerosis of Chronic Kidney Disease

NCT ID: NCT01458158

Last Updated: 2015-02-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-10-31

Study Completion Date

2016-05-31

Brief Summary

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The purpose of this study is to determine whether matrix metalloproteinases are associated with atherosclerosis in the different stages of chronic kidney disease.

Detailed Description

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The purpose of this study is to determine the correlation of matrix metalloproteinases and atherosclerosis of chronic kidney disease. Patients with diabetes mellitus type 2,as a non-inflammatory leading cause of end stage renal failure and patients with chronic glomerulonephritis and similar course of proteinuria,as an inflammatory leading cause of end stage renal failure are enrolled.

Conditions

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Diabetic Nephropathy

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Diabetic nephropathy

Diabetic nephropathy in patients with type 2 diabetes

No interventions assigned to this group

chronic glomerulonephritis

chronic glomerulonephritis in patients without diabetes mellitus

No interventions assigned to this group

controls

participants without diabetic nephropathy and chronic glomerulonephritis

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Chronic kidney disease
* Diabetes mellitus type 2

Exclusion Criteria

* Malignancy
Minimum Eligible Age

50 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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AHEPA University Hospital

OTHER

Sponsor Role collaborator

Aristotle University Of Thessaloniki

OTHER

Sponsor Role lead

Responsible Party

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Grigorios G. DIMAS

Doctor/PhD Candidate

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Grigorios G. Dimas, MD

Role: PRINCIPAL_INVESTIGATOR

AHEPA University Hospital,Medical School of Aristotle University of Thessaloniki

Locations

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AHEPA University Hospital, Medical School of Aristotle University of Thessaloniki

Thessaloniki, , Greece

Site Status RECRUITING

Countries

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Greece

Central Contacts

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Grigorios G. Dimas

Role: CONTACT

+0030 6972321534

Other Identifiers

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31-8-2010

Identifier Type: OTHER

Identifier Source: secondary_id

A13749

Identifier Type: -

Identifier Source: org_study_id

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