Creation of a Biological Collection for Medical Research Purposes for Patients at the Reference Center for Rare Diseases of the Blood Vessels of the Brain and Eye at Lariboisière Hospital

NCT ID: NCT07264972

Last Updated: 2025-12-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-21

Study Completion Date

2027-07-31

Brief Summary

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The aim of establishing a biological collection associated with the existing rare cerebral vascular disease cohort is to identify new prognostic or disease progression biomarkers that could improve patient care or identify new therapeutic targets.

Detailed Description

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Conditions

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Cerebrovascular Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with rare cerebrovascular disease

additional samples for research purposes

Intervention Type OTHER

Blood and urine sampling

Interventions

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additional samples for research purposes

Blood and urine sampling

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Confirmed diagnosis of a rare cerebral vascular disease of the brain, including:

Familial intracranial aneurysms, cerebral amyloid angiopathy, CADASIL, familial cerebral cavernoma, familial cervical or intracranial artery dissection, vascular leukoencephalopathy (hereditary), familial hemiplegic migraine, cerebral arteriovenous malformation, moya-moya, cerebral venous thrombosis, hereditary retinal tortuosity, cerebro-retinal vasculopathies, other known rare diseases, or other rare diseases that are undetermined or not yet described.

* Participation in the MVCR cohort
* Adults \>18 years old
* Affiliation with French social security or beneficiary - Signature of informed consent

Exclusion Criteria

* Incompatibility with long-term follow-up at CERVCO
* Patient under guardianship/conservatorship
* Pregnant or breastfeeding women
* Patient under AME
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Lariboisière hospital

Paris, , France

Site Status

Countries

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France

Other Identifiers

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APHP200773

Identifier Type: -

Identifier Source: org_study_id

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