Comparison Between the Efficacy of Ultrasound-guided Erector Spinae Plane Block and Conventional Treatment for Pain Management in Patients With Post-herpetic Neuralgia

NCT ID: NCT07256145

Last Updated: 2025-12-01

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 60 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-08-01
• Study Completion Date: 2026-03-01

Brief Summary

The present study aims to evaluate the efficacy of ultrasound-guided erector spinae plane block with steroids to relieve pain in cases of post-herpetic neuralgia, patient satisfaction, and record any complications post-injection.

Detailed Description

The current study will be conducted as a single-blinded prospective randomized controlled study to evaluate the efficacy of ultrasound-guided erector spinae plane block with steroids to relieve pain in cases of post-herpetic neuralgia.

All patients will be evaluated by:

• Full history taking: including age, sex, presence of co-morbid conditions as well as the presenting complaint.
• Clinical examination and routine lab investigations that include:

• Complete blood count (CBC).
• Fasting blood glucose (FBG).
• Coagulation profile (bleeding time, prothrombin time, prothrombin activity, international normalized ratio).

Measurements:

Patients will be followed up at 24 hours, 1 week, and 6 weeks after injection.

The following measurements will be recorded:

1. Pain will be assessed pre- and post-injection using VAS score at 24 hours, 1 week, and 6 weeks post-injection.

2. Need for analgesic intake post-injection will be assessed at the follow-up periods.

3. Patient satisfaction using the SAPS score.

4. Complications post-injection as pain, irritation or infection will be assessed.

Conditions

Post-Herpetic Neuralgia

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

Injection group

Group Type: EXPERIMENTAL

erector spinae plane block

Intervention Type: PROCEDURE

erector spinae plane block with steroids

conventional group

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

erector spinae plane block

erector spinae plane block with steroids

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Patients with post-herpetic neuralgia not responding to medical treatment.

Exclusion Criteria

• 1- Patient refusal 2- Age less than 20 years or older than 70 years. 3- Systemic Infection. 4-Patients with dementia or other diseases that could have impaired their memory or cognitive function.

5- Immunocompromised patients, severe osteoporosis, and uncontrolled diabetes mellitus.

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 70 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Alexandria University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Alexandria University

Alexandria, Aleexandria, Egypt

Site Status: RECRUITING

Countries

Egypt

Facility Contacts

yasmine ragab elsayed, MD

Role: primary

y_elsayed16@alexmed.edu.eg

00201001972418

Other Identifiers

0307429

Identifier Type: -

Identifier Source: org_study_id