Interscalene Versus Infraspinatus-Teres Minor Blocks for Arthroscopic Shoulder Surgery

NCT ID: NCT07253740

Last Updated: 2026-01-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-01-01

Study Completion Date

2026-05-02

Brief Summary

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This randomized controlled trial aims to compare the effectiveness of interscalene (ISB) and infraspinatus-teres minor (ITM) blocks for postoperative analgesia in patients undergoing elective arthroscopic shoulder surgery. The primary outcome is total 24-hour opioid consumption. Secondary outcomes include pain scores, hemidiaphragmatic paresis incidence and severity, duration of analgesia, and changes in lung function. Participants are randomized into ISB or ITM groups; blocks are performed under ultrasound guidance. Postoperative pain is managed with patient controlled analgesia(PCA).

Detailed Description

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This is a single-center, prospective, randomized clinical trial designed to compare the efficacy of Interscalene Brachial Plexus Block (ISB) and Infraspinatus-Teres Minor (ITM) interfascial block in patients undergoing elective unilateral arthroscopic shoulder surgery. The primary objective is to compare total 24-hour postoperative opioid consumption. Secondary objectives include the and pain scores, incidence and severity of hemidiaphragmatic paresis, duration of analgesia (from block completion to initiation of IV PCA), and postoperative pulmonary function changes.

This study aims to determine whether the ITM block provides comparable perioperative analgesia to the ISB block while potentially reducing hemidiaphragmatic paresis and pulmonary compromise.

Conditions

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Arthroscopic Shoulder Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors
The anesthesiologist performing the blocks is aware of the group allocation; all other staff and outcome assessors are blinded.

Study Groups

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Interscalene Brachial Plexus Block (ISB)

Patients will receive ISB under ultrasound guidance prior to arthroscopic shoulder surgery using 15 ml 0.25% bupivacaine.

Group Type EXPERIMENTAL

Interscalene Brachial Plexus Block (ISB)

Intervention Type PROCEDURE

Patients receive ultrasound-guided ISB before arthroscopic shoulder surgery. After sedation with IV midazolam, 15 ml of 0.25% bupivacaine is injected using a 22 Gauge 50 mm needle with posterior in-plane approach, targeting C5-C6 roots.

Infraspinatus-Teres Minor Block (ITM)

Patients will receive TM block under ultrasound guidance using 25 ml 0.25% bupivacaine between infraspinatus and teres minor muscles.

Group Type EXPERIMENTAL

Infraspinatus-Teres Minor Block (ITM)

Intervention Type PROCEDURE

Patients receive ultrasound-guided ITM interfascial block in sitting position before surgery. Using a 22 Gauge 10 mm needle, 25 ml of 0.25% bupivacaine is injected between infraspinatus and teres minor muscles via out-of-plane or in-plane hydrodissection.

Interventions

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Interscalene Brachial Plexus Block (ISB)

Patients receive ultrasound-guided ISB before arthroscopic shoulder surgery. After sedation with IV midazolam, 15 ml of 0.25% bupivacaine is injected using a 22 Gauge 50 mm needle with posterior in-plane approach, targeting C5-C6 roots.

Intervention Type PROCEDURE

Infraspinatus-Teres Minor Block (ITM)

Patients receive ultrasound-guided ITM interfascial block in sitting position before surgery. Using a 22 Gauge 10 mm needle, 25 ml of 0.25% bupivacaine is injected between infraspinatus and teres minor muscles via out-of-plane or in-plane hydrodissection.

Intervention Type PROCEDURE

Other Intervention Names

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Interscalene Nerve Block

Eligibility Criteria

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Inclusion Criteria

* The American Society of Anesthesiologists I-III
* Scheduled for elective unilateral arthroscopic shoulder surgery
* Provide written informed consent

Exclusion Criteria

* Refusal to participate
* Allergy to study drugs
* Severe cardiac, renal, or hepatic disease
* Neurological deficit or neuropathy
* Anticoagulant therapy
* Pre-existing respiratory dysfunction
* Chronic shoulder pain or planned open surgery
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ataturk University

OTHER

Sponsor Role lead

Responsible Party

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Ali Ahiskalioglu

Principal Investigator Ali Ahıskalıoğlu

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ali Ahıskalıoğlu, Professor

Role: PRINCIPAL_INVESTIGATOR

Ataturk University Department of Anesthesiology and Reanimation

Locations

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Ataturk University

Erzurum, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Ali Ahıskalıoğlu, Professor

Role: CONTACT

+90-554-442-48-31

Ramazan Altunkaynak, MD

Role: CONTACT

+90-553-811-95-44

Facility Contacts

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Ali Ahıskalıoğlu, Professor

Role: primary

+90-544-442-48-31

Ramazan Altunkaynak, MD

Role: backup

+90-553-811-95-44

References

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Renes SH, Rettig HC, Gielen MJ, Wilder-Smith OH, van Geffen GJ. Ultrasound-guided low-dose interscalene brachial plexus block reduces the incidence of hemidiaphragmatic paresis. Reg Anesth Pain Med. 2009 Sep-Oct;34(5):498-502. doi: 10.1097/AAP.0b013e3181b49256.

Reference Type BACKGROUND
PMID: 19920426 (View on PubMed)

Kim SH, Yeo IS, Jang J, Jung HE, Chun YM, Yang HM. Infraspinatus-teres minor (ITM) interfascial block: a novel approach for combined suprascapular and axillary nerve block. Reg Anesth Pain Med. 2024 Jan 11;49(1):67-72. doi: 10.1136/rapm-2023-104738.

Reference Type BACKGROUND
PMID: 37491150 (View on PubMed)

Kang R, Jeong JS, Chin KJ, Yoo JC, Lee JH, Choi SJ, Gwak MS, Hahm TS, Ko JS. Superior Trunk Block Provides Noninferior Analgesia Compared with Interscalene Brachial Plexus Block in Arthroscopic Shoulder Surgery. Anesthesiology. 2019 Dec;131(6):1316-1326. doi: 10.1097/ALN.0000000000002919.

Reference Type BACKGROUND
PMID: 31490292 (View on PubMed)

Teske LG, Pill SG, Lutz A, Thigpen CA, Shanley E, Adams KJ, Bohon H, Graham GD, Marston G, Walker KB, Kissenberth MJ. Single shot interscalene regional anesthesia provides noninferior analgesia and decreased complications compared with an indwelling catheter for arthroscopic and reconstructive shoulder surgery. J Shoulder Elbow Surg. 2022 Jun;31(6S):S152-S157. doi: 10.1016/j.jse.2022.02.004. Epub 2022 Mar 15.

Reference Type BACKGROUND
PMID: 35301140 (View on PubMed)

Benyamin R, Trescot AM, Datta S, Buenaventura R, Adlaka R, Sehgal N, Glaser SE, Vallejo R. Opioid complications and side effects. Pain Physician. 2008 Mar;11(2 Suppl):S105-20.

Reference Type BACKGROUND
PMID: 18443635 (View on PubMed)

Luan H, Hao C, Li H, Zhang X, Zhao Z, Zhu P. Effect of interscalene brachial plexus block with dexmedetomidine and ropivacaine on postoperative analgesia in patients undergoing arthroscopic shoulder surgery: a randomized controlled clinical trial. Trials. 2023 Jun 12;24(1):392. doi: 10.1186/s13063-023-07292-2.

Reference Type BACKGROUND
PMID: 37308994 (View on PubMed)

Ahiskalioglu A, Karapinar YE, Dagci Y, Yayik AM, Ciftci B, Tulgar S. An alternative sonographic approach to infraspinatus-teres minor interfascial plane block: make it easy. Minerva Anestesiol. 2025 Apr;91(4):359-361. doi: 10.23736/S0375-9393.24.18697-X. Epub 2025 Feb 6. No abstract available.

Reference Type BACKGROUND
PMID: 39912574 (View on PubMed)

Other Identifiers

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ATAUNISHOULDER

Identifier Type: -

Identifier Source: org_study_id

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