Detection of Microplastics in Patients With Periodontitis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

25 participants

Study Classification

OBSERVATIONAL

Study Start Date

2026-02-01

Study Completion Date

2028-02-01

Brief Summary

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Plastic particles known as microplastics are now a ubiquitous part of the environment. Human exposure to microplastics occurs through the consumption of contaminated food and polluted air, which affect the intestinal system. Several studies have detected the presence of microplastics in various parts of the human digestive system, e.g., in feces. Unfortunately, little is known about the presence of microplastics in the mouth as the primary part of the digestive system. Periodontal pockets can be considered an ideal deposition site for microplastics. Since microplastics are suspected of being an immunomodulatory factor, there is great interest in their presence in subgingival plaque and their possible exacerbation of chronic inflammatory diseases such as periodontitis. The following study aims to clarify the presence, classification, and concentration of microplastics in subgingival plaque. No comparable study has been identified to date.

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Detailed Description

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Conditions

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Periodontal Diseases Periodontitis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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patients with periodontitis, stage 3 or 4

Status assessment with supragingival cleaning Sample collection with sterile universal curette (steel) from the bottom of the pockets of the 4 deepest gum pockets (ST \>= 5mm) pooled in ultrapure water

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Adults aged 18 and over
* Gender: Female / male / diverse
* Patients

* who have been diagnosed with stage III and IV periodontitis.
* who have not yet started periodontal treatment.
* who still have at least 20 teeth. Providing written consent to participate in the study.