Interdental Plaque Reduction and Periodontitis

NCT ID: NCT04527913

Last Updated: 2022-11-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-09-30

Study Completion Date

2020-08-31

Brief Summary

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To determine the efficacy of four different oral hygiene protocols involving adjunctive interdental cleaning devices in periodontal patients in terms of plaque and gingival inflammatory scores.

Detailed Description

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Patients included in the study will undergo a thorough clinical examination aiming at collecting all the data desired: periodontal parameters of Probing Pocket Depth (PPD), presence of recession of the gingival margin (Rec) and full mouth plaque score (FMPS) will be recorded on six sites/tooth by a single calibrated examiner using a University of North Carolina (UNC) 15-mm periodontal probe by a calibrated examiner blind to group allocation.

Gingival index (GI) and angulated bleeding score (AngBS) will be recorded at four sites/tooth.

For GI the following scale will be used:

0 normal appearance of gingiva, no bleeding, no inflammation;

1. slight change and moderate edema with slight change in texture, no bleeding, mild inflammation;
2. redness hypertrophy, or edema and glazing, bleeding on probing, moderate inflammation;
3. marked redness, hypertrophy, or edema, ulceration, spontaneous bleeding, severe inflammation.

For AngBS the following scale will be used:

0: no bleeding;

1. bleeding upon probe stimulation;
2. spontaneous bleeding

Consequently, interdental plaque score (IPS), interdental gingival index (IGI), and interdental angulated bleeding score (IAngBI) will be calculated.

Patients will be followed through a five-week period. The timepoints will be the following: T -7 (oral hygiene instructions), T0 (professional supragingival scaling and polishing), T14, T28.

Conditions

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Periodontitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Single-centre randomized, parallel design, clinical trial with a five-week follow-up
Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Investigators Outcome Assessors
Center will enroll probands, assigning a unique study subject number and allocating an opaque randomization envelope.

Study Groups

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Control group

15 patients receiving oral hygiene instructions as determined by their group allocation (use of manual toothbrush alone)

Group Type EXPERIMENTAL

One session of professional supragingival scaling and polishing

Intervention Type PROCEDURE

A session of professional supragingival scaling and polishing: instrumentation will be performed by a trained dental hygienist/periodontist with great care in performing exclusively coronal maneuver. No instrumentation or exploring of the gingival crevice/ sulcus will be performed.

Oral Hygiene Instruction (OHI)

Intervention Type PROCEDURE

OHI will be given focusing on manual toothbrushing and will be given only once at timepoint T-7. No further formal OH instructions will be given, unless specifically asked by the patient.

OHI will be delivered by trained dental hygienist/periodontist.

Test group 1

15 patients receiving oral hygiene instructions as determined by their group allocation (manual toothbrush plus dental floss)

Group Type EXPERIMENTAL

Interdental Oral Hygiene Instruction (Int-OHI)

Intervention Type BEHAVIORAL

Int-OHI will be given focusing on the interdental device of the allocated group for each patient and will be given only once at timepoint T-7. No further formal Int-OH instructions will be given, unless specifically asked by the patient.

Int-OHI will be delivered by trained dental hygienist/periodontist.

One session of professional supragingival scaling and polishing

Intervention Type PROCEDURE

A session of professional supragingival scaling and polishing: instrumentation will be performed by a trained dental hygienist/periodontist with great care in performing exclusively coronal maneuver. No instrumentation or exploring of the gingival crevice/ sulcus will be performed.

Oral Hygiene Instruction (OHI)

Intervention Type PROCEDURE

OHI will be given focusing on manual toothbrushing and will be given only once at timepoint T-7. No further formal OH instructions will be given, unless specifically asked by the patient.

OHI will be delivered by trained dental hygienist/periodontist.

Test group 2

15 patients receiving oral hygiene instructions as determined by their group allocation (manual toothbrush plus interdental brushes)

Group Type EXPERIMENTAL

Interdental Oral Hygiene Instruction (Int-OHI)

Intervention Type BEHAVIORAL

Int-OHI will be given focusing on the interdental device of the allocated group for each patient and will be given only once at timepoint T-7. No further formal Int-OH instructions will be given, unless specifically asked by the patient.

Int-OHI will be delivered by trained dental hygienist/periodontist.

One session of professional supragingival scaling and polishing

Intervention Type PROCEDURE

A session of professional supragingival scaling and polishing: instrumentation will be performed by a trained dental hygienist/periodontist with great care in performing exclusively coronal maneuver. No instrumentation or exploring of the gingival crevice/ sulcus will be performed.

Oral Hygiene Instruction (OHI)

Intervention Type PROCEDURE

OHI will be given focusing on manual toothbrushing and will be given only once at timepoint T-7. No further formal OH instructions will be given, unless specifically asked by the patient.

OHI will be delivered by trained dental hygienist/periodontist.

Test group 3

15 patients receiving oral hygiene instructions as determined by their group allocation (manual toothbrush plus rubber interdental picks)

Group Type EXPERIMENTAL

Interdental Oral Hygiene Instruction (Int-OHI)

Intervention Type BEHAVIORAL

Int-OHI will be given focusing on the interdental device of the allocated group for each patient and will be given only once at timepoint T-7. No further formal Int-OH instructions will be given, unless specifically asked by the patient.

Int-OHI will be delivered by trained dental hygienist/periodontist.

One session of professional supragingival scaling and polishing

Intervention Type PROCEDURE

A session of professional supragingival scaling and polishing: instrumentation will be performed by a trained dental hygienist/periodontist with great care in performing exclusively coronal maneuver. No instrumentation or exploring of the gingival crevice/ sulcus will be performed.

Oral Hygiene Instruction (OHI)

Intervention Type PROCEDURE

OHI will be given focusing on manual toothbrushing and will be given only once at timepoint T-7. No further formal OH instructions will be given, unless specifically asked by the patient.

OHI will be delivered by trained dental hygienist/periodontist.

Interventions

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Interdental Oral Hygiene Instruction (Int-OHI)

Int-OHI will be given focusing on the interdental device of the allocated group for each patient and will be given only once at timepoint T-7. No further formal Int-OH instructions will be given, unless specifically asked by the patient.

Int-OHI will be delivered by trained dental hygienist/periodontist.

Intervention Type BEHAVIORAL

One session of professional supragingival scaling and polishing

A session of professional supragingival scaling and polishing: instrumentation will be performed by a trained dental hygienist/periodontist with great care in performing exclusively coronal maneuver. No instrumentation or exploring of the gingival crevice/ sulcus will be performed.

Intervention Type PROCEDURE

Oral Hygiene Instruction (OHI)

OHI will be given focusing on manual toothbrushing and will be given only once at timepoint T-7. No further formal OH instructions will be given, unless specifically asked by the patient.

OHI will be delivered by trained dental hygienist/periodontist.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* males or females of age range between 18 and 70 years,
* good health status,
* presence of at least 20 natural teeth
* residual periodontal pockets with PPD≥4mm, in need of specific oral hygiene regimen.

Exclusion Criteria

* pregnancy or breast-feeding,
* indication to antibiotic therapy prior to treatment,
* chronic infections,
* systemic diseases (including cardiovascular, pulmonary, cerebral, and metabolic diseases),
* not willing to give a consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Pisa

OTHER

Sponsor Role lead

Responsible Party

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Filippo Graziani, DDS MClinDent PhD

Full Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University Hospital of Pisa

Pisa, , Italy

Site Status

Countries

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Italy

Other Identifiers

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Periobrush

Identifier Type: -

Identifier Source: org_study_id

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