Digital Intervention for Adults With Misophonia: A Randomized Controlled Trial

NCT ID: NCT07220941

Last Updated: 2025-10-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-31

Study Completion Date

2027-02-28

Brief Summary

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The goal of this clinical trial is to test an online intervention for adults with misophonia. The main questions it aims to answer are:

1. Is the online intervention effective, compared to a waitlist control condition?
2. Is the online intervention acceptable to use?

Participants will be randomized into either the online intervention or waitlist control condition:

1. Participants in the intervention condition will be asked to complete an 8 module acceptance and commitment therapy (ACT) program for misophonia and 5 surveys over 4 months.
2. Participants in the waitlist condition will be asked to complete 5 surveys over 4 months, and will receive access to the intervention once the study is complete.

Detailed Description

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Misophonia, characterized by intense emotional reactions to specific sounds, significantly impacts daily functioning and quality of life. Acceptance and Commitment Therapy (ACT) has shown promise in addressing misophonia symptoms by fostering psychological flexibility. While recent intervention studies demonstrate the efficacy of ACT for misophonia, accessible and scalable treatment options remain scarce. This study aims to address this gap by developing and evaluating a fully automated, online ACT-based digital mental health intervention for misophonia. We will compare the intervention to a delayed treatment group in a sample of 100 adults meeting clinical criteria for misophonia. Outcomes will include misophonia symptoms, quality of life, general distress, and psychological flexibility, assessed at baseline, mid-intervention, post-intervention, and one- and two-month follow-up. Multilevel modeling will test time by condition interactions to examine the efficacy and feasibility of an online ACT-based intervention. This fully automated online intervention aims to provide accessible, evidence-based treatment for individuals with misophonia, laying groundwork for future, larger-scale studies and public dissemination.

Conditions

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Misophonia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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ACT online program

Participants will complete the 8-module fully automated digital intervention based in acceptance and commitment therapy (ACT).

Group Type EXPERIMENTAL

Acceptance and commitment therapy

Intervention Type BEHAVIORAL

Participants will complete the 8-module fully automated digital intervention based in acceptance and commitment therapy (ACT). The digital program is based off of an ACT protocol developed in a prior randomized controlled trial and adapted for digital self-help use (Bowers et al., 2024). Modules focus on focus on acceptance, cognitive defusion, present moment awareness, values clarification, and functional adaptations.

Waitlist Control

Waitlist condition; assessment only.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Acceptance and commitment therapy

Participants will complete the 8-module fully automated digital intervention based in acceptance and commitment therapy (ACT). The digital program is based off of an ACT protocol developed in a prior randomized controlled trial and adapted for digital self-help use (Bowers et al., 2024). Modules focus on focus on acceptance, cognitive defusion, present moment awareness, values clarification, and functional adaptations.

Intervention Type BEHAVIORAL

Other Intervention Names

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ACT

Eligibility Criteria

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Inclusion Criteria

* Currently meet clinical impairment for misophonia.
* At least 18 years old.
* Fluent English speakers.
* Currently live or reside in the United States

Exclusion Criteria

* Currently receiving alternative psychotherapy for misophonia.
* Currently modifying or starting psychotropic medication (within 30 days of starting the study).
* Any psychological and/or neurological impairments that would preclude someone from participating in the study (e.g.,active self-harm or psychosis)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Misophonia Research Fund

OTHER

Sponsor Role collaborator

Utah State University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Emily M Bowers, M.S.

Role: PRINCIPAL_INVESTIGATOR

Utah State University

Locations

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Utah State University

Logan, Utah, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Emily M Bowers, M.S.

Role: CONTACT

781-686-6091

Michael P Twohig, PhD

Role: CONTACT

435-265-8933

Facility Contacts

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Emily M Bowers, M.S.

Role: primary

781-686-6091

Other Identifiers

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15239

Identifier Type: -

Identifier Source: org_study_id

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