Pilot Investigation of Dual Energy CT Imaging on an Online Adaptive Radiation Therapy System

NCT ID: NCT07219134

Last Updated: 2025-10-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-06-06

Study Completion Date

2027-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study is being done to see if researchers can find a better way to image a patient's tumor during radiation treatment.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Genitourinary System Carcinoma Malignant Pelvic Neoplasm

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Observational

Patients undergo lower beam energy CBCT scan once during standard of care radiation therapy on study.

Non-Interventional Study

Intervention Type OTHER

Non-interventional study

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Non-Interventional Study

Non-interventional study

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* \* Patients with pelvis or genitourinary (GU) cancer requiring standard of care radiotherapy treatment

* All adults, defined as individuals of 18 years of age or greater
* Radiotherapy treatment will be performed on the Varian Ethos radiotherapy system
* Ability to understand and the willingness to sign a written informed consent

Exclusion Criteria

* \* Minors, defined as individuals less than 18 years of age

* Pregnant or nursing female
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Varian Medical Systems, Inc.

UNKNOWN

Sponsor Role collaborator

University of Michigan Rogel Cancer Center

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Robert Dess

Role: PRINCIPAL_INVESTIGATOR

University of Michigan Rogel Cancer Center

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Cancer AnswerLine

Role: CONTACT

1-800-865-1125

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Cancer AnswerLine

Role: primary

800-865-1125

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

NCI-2025-03767

Identifier Type: REGISTRY

Identifier Source: secondary_id

HUM00259510

Identifier Type: OTHER

Identifier Source: secondary_id

UMCC 2024.027

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Functional Imaging in Lung SBRT
NCT03121300 COMPLETED