Evaluating the Feasibility and Preliminary Effects of BE+
NCT ID: NCT07214441
Last Updated: 2025-10-09
Study Results
Results pending
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
Recruitment Status
ENROLLING_BY_INVITATION
Clinical Phase
NA
Total Enrollment
20 participants
Study Classification
INTERVENTIONAL
Study Start Date
2025-08-15
Study Completion Date
2026-05-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
This non-randomized, single group study will test a 12-week, behavioral intervention for physical activity and stress management for survivors of non-small cell lung cancer (NSCLC) and a partner (family member or friend). The goals of this intervention, Breathe Easier+ (BE+), are to increase overall physical activity and overall fitness and to reduce symptoms (fatigue, breathlessness, sleep, and stress).
The aim of this study is to evaluate the enrollment, retention, adherence, participation, and acceptability of the 12-week BE+ among NSCLC survivors and their partners. The study also aims to:
1. Explore preliminary intervention effects of BE+ on increasing physical activity and overall fitness (measured by 7-day Fitbit wear, step-in-place test, chair sit-and-stand, arm curl test, and balance test) from baseline to post-intervention among NSCLC survivors and their partners.
2. Explore preliminary effects of BE+ for improvement in stress response, symptom burden (fatigue, dyspnea), sleep, and HRQL from baseline to post-intervention among NSCLC survivors and their partners.
Participants will receive education, social support, coaching, a guided walking program, supervised resistance training (RT), and meditations delivered via digital technology (tablet, smartphone, and Fitbit).
The aim of this study is to evaluate the enrollment, retention, adherence, participation, and acceptability of the 12-week BE+ among NSCLC survivors and their partners. The study also aims to:
1. Explore preliminary intervention effects of BE+ on increasing physical activity and overall fitness (measured by 7-day Fitbit wear, step-in-place test, chair sit-and-stand, arm curl test, and balance test) from baseline to post-intervention among NSCLC survivors and their partners.
2. Explore preliminary effects of BE+ for improvement in stress response, symptom burden (fatigue, dyspnea), sleep, and HRQL from baseline to post-intervention among NSCLC survivors and their partners.
Participants will receive education, social support, coaching, a guided walking program, supervised resistance training (RT), and meditations delivered via digital technology (tablet, smartphone, and Fitbit).
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Feasibility of a Hybrid Delivery of Home-based Cluster Set Resistance Training in Lung Cancer
NCT05014035
Non Small Cell Lung Cancer
Resistance Exercise
COMPLETED
NA
Resistance Training in Lung Cancer Patients on Chemotherapy
NCT01130714
Inflammation
Lung Cancer
COMPLETED
NA
Feasibility of Exercise With Post-Op Lung Cancer Patients
NCT00636571
Non-Small Cell Lung Cancer
COMPLETED
NA
New York Better Breathing Study
NCT06869447
Localized Lung Carcinoma
Stage I Lung Cancer AJCC v8
Stage II Lung Cancer AJCC v8
+1 more
RECRUITING
NA
Feasibility of an Activity Regimen in Patients With Advanced Stage Lung Cancer
NCT03352245
Lung Neoplasm Malignant
COMPLETED
NA
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Lung cancer is the second-most diagnosed malignancy, accounting for more annual deaths than breast, prostate, and colorectal cancers combined. Approximately 80% of lung cancer diagnoses are non-small-cell lung cancer (NSCLC), 42% will present with localized disease and 58% will present with advanced disease. Scientific advances have led to improved 5-year survival rates. These advances are projected to improve, meaning that survivors of NSCLC will live longer. However, the extent of thoracic resection, radiation, chemotherapy, and immunotherapy treatment; common comorbid conditions like COPD (chronic obstructive pulmonary disease); and health behaviors exacerbate physical and emotional health burdens. Research has yet to address the management of physical deconditioning and unresolved symptoms (e.g., dyspnea, fatigue) in long-term survivors of lung cancer, both of which negatively impact health-related quality of life (HRQL). Self-management interventions that target lifestyle behaviors such as physical activity and stress reduction have demonstrated meaningful benefit in managing symptom burden. Additionally, scientific consensus supports the use of resistance training (RT) to mitigate functional decline from physical deconditioning by increasing muscular strength and endurance. However, frequently NSCLC survivors are sedentary or insufficiently active.
Lifestyle behaviors tend to cluster in families and social networks; thus, family members and friends of survivors are also at risk of poor health. An emerging consensus corroborates the inclusion of family and friends ("partners") of cancer survivors in self-management interventions. In this proposal, a partner is anyone the survivor considers a supportive person. Partners are critical sources of all types of social support across the cancer continuum. Importantly, partners must cope with their own concerns, including uncertainty surrounding the survivor's illness, fear of losing their partner, and the impact of their own health behaviors. Together, survivors and their partners may benefit significantly from a dyad-based lifestyle behavior intervention that supports physical and emotional health.
This research team has conducted extensive formative and preliminary research to develop a dyad-based intervention for NSCLC survivors and their partners. Early on, participants clearly indicated a preference for home-based, family- and safety-oriented interventions. Most recently, participants demonstrated the feasibility and preliminary effectiveness of a 12-week, dyad-based, telephone-delivered, self-management intervention known as Breathe Easier (BE), featuring mindfulness-based breathing exercises, meditation, and a walking program for dyads (N = 40; 20 dyads). Another study involved testing an RT program tailored to survivors only (n = 14). Feasibility and acceptability were strong and indicated positive improvements involving symptom burden and physical functioning.
Recognizing that evidence supports a multimodal approach, our research team aims to expand the BE intervention by integrating home-based RT via digital technology. The revised intervention will be known as BE+ and will include stage IV survivors to better understand the feasibility of this subgroup.
Theoretical Approach: The ORBIT model, which is a systematic framework for developing behavioral interventions, was used to develop a chain of evidence for the BE+ intervention program. BE+ is also built on the individual and family self-management theory (IFSMT), which proposes that successful change in health behavior self-management after a diagnosis of lung cancer requires active involvement by the survivor coupled with partner support. IFSMT encompasses three broad dimensions (context, process, outcomes) and promotes self-regulation, self-efficacy, and social support. The context dimension may impact individual and partner engagement in the self-management process and, therefore, the outcomes. Within the process dimension, self-regulation of the self-management of behaviors requires active involvement. Social support enhances the capacity to change and influences collaboration among dyads. The program components of BE+ enhance these three factors-leading to improved health behaviors. The behaviors of individuals in close, personal relationships are interdependent, and the actions of one person continuously affect the other's actions.
Design: A 12-week, non-randomized, one group pre-post feasibility study piloted among NSCLC survivors and their partners.
A purposive sample of 10 dyads (N = 20 participants) will be recruited from two cancer treatment centers in South Carolina. A partner, defined as a relative or close friend (i.e., spouse, sibling, adult child, neighbor), will be required for enrollment.
Analysis Plan: A power analysis will not be performed as this feasibility study does not warrant formal hypothesis testing, and all statistical tests will use an α cut point of 0.10 for meaningful preliminary differences. This nontraditional cut point (vs. α = 0.05) is more lenient due to the feasibility study design. Data analysis software will be used to obtain information regarding step count, and sleep SAS 9.4 (Cary, NC) software will be used to calculate means (± SD) and frequencies for demographic data. Normality will be checked using histogram and Q-Q plots combined with skewness and kurtosis statistics. When the outcome is normally distributed, independent t-tests will be performed to assess subset differences between survivors and partners to evaluate preliminary effects. Equal variances will be determined using the Folded F test, and thus the pooled version of the independent t-test will be used to determine preliminary meaningful differences. Then repeated measures ANOVA will be used to compare means among three time points. If normality is violated, the Mann-Whitney U Test will be used to compare outcome differences between survivors and partners, and Friedman's ANOVA by ranks will be used to evaluate the differences among three time points.
Exit interviews will be audio-recorded and professionally transcribed. The lead investigator will review transcripts and audio recordings to confirm accuracy. Thematic analysis will be used to analyze the transcripts following a six-phase approach: (1) become familiar with the data, (2) generate codes, (3) search for themes, (4) review themes, (5) define or name themes, (6) report findings and analysis.64 Transcripts will be iteratively analyzed by the research team to reach a consensus on codes, categories, and themes.
Lifestyle behaviors tend to cluster in families and social networks; thus, family members and friends of survivors are also at risk of poor health. An emerging consensus corroborates the inclusion of family and friends ("partners") of cancer survivors in self-management interventions. In this proposal, a partner is anyone the survivor considers a supportive person. Partners are critical sources of all types of social support across the cancer continuum. Importantly, partners must cope with their own concerns, including uncertainty surrounding the survivor's illness, fear of losing their partner, and the impact of their own health behaviors. Together, survivors and their partners may benefit significantly from a dyad-based lifestyle behavior intervention that supports physical and emotional health.
This research team has conducted extensive formative and preliminary research to develop a dyad-based intervention for NSCLC survivors and their partners. Early on, participants clearly indicated a preference for home-based, family- and safety-oriented interventions. Most recently, participants demonstrated the feasibility and preliminary effectiveness of a 12-week, dyad-based, telephone-delivered, self-management intervention known as Breathe Easier (BE), featuring mindfulness-based breathing exercises, meditation, and a walking program for dyads (N = 40; 20 dyads). Another study involved testing an RT program tailored to survivors only (n = 14). Feasibility and acceptability were strong and indicated positive improvements involving symptom burden and physical functioning.
Recognizing that evidence supports a multimodal approach, our research team aims to expand the BE intervention by integrating home-based RT via digital technology. The revised intervention will be known as BE+ and will include stage IV survivors to better understand the feasibility of this subgroup.
Theoretical Approach: The ORBIT model, which is a systematic framework for developing behavioral interventions, was used to develop a chain of evidence for the BE+ intervention program. BE+ is also built on the individual and family self-management theory (IFSMT), which proposes that successful change in health behavior self-management after a diagnosis of lung cancer requires active involvement by the survivor coupled with partner support. IFSMT encompasses three broad dimensions (context, process, outcomes) and promotes self-regulation, self-efficacy, and social support. The context dimension may impact individual and partner engagement in the self-management process and, therefore, the outcomes. Within the process dimension, self-regulation of the self-management of behaviors requires active involvement. Social support enhances the capacity to change and influences collaboration among dyads. The program components of BE+ enhance these three factors-leading to improved health behaviors. The behaviors of individuals in close, personal relationships are interdependent, and the actions of one person continuously affect the other's actions.
Design: A 12-week, non-randomized, one group pre-post feasibility study piloted among NSCLC survivors and their partners.
A purposive sample of 10 dyads (N = 20 participants) will be recruited from two cancer treatment centers in South Carolina. A partner, defined as a relative or close friend (i.e., spouse, sibling, adult child, neighbor), will be required for enrollment.
Analysis Plan: A power analysis will not be performed as this feasibility study does not warrant formal hypothesis testing, and all statistical tests will use an α cut point of 0.10 for meaningful preliminary differences. This nontraditional cut point (vs. α = 0.05) is more lenient due to the feasibility study design. Data analysis software will be used to obtain information regarding step count, and sleep SAS 9.4 (Cary, NC) software will be used to calculate means (± SD) and frequencies for demographic data. Normality will be checked using histogram and Q-Q plots combined with skewness and kurtosis statistics. When the outcome is normally distributed, independent t-tests will be performed to assess subset differences between survivors and partners to evaluate preliminary effects. Equal variances will be determined using the Folded F test, and thus the pooled version of the independent t-test will be used to determine preliminary meaningful differences. Then repeated measures ANOVA will be used to compare means among three time points. If normality is violated, the Mann-Whitney U Test will be used to compare outcome differences between survivors and partners, and Friedman's ANOVA by ranks will be used to evaluate the differences among three time points.
Exit interviews will be audio-recorded and professionally transcribed. The lead investigator will review transcripts and audio recordings to confirm accuracy. Thematic analysis will be used to analyze the transcripts following a six-phase approach: (1) become familiar with the data, (2) generate codes, (3) search for themes, (4) review themes, (5) define or name themes, (6) report findings and analysis.64 Transcripts will be iteratively analyzed by the research team to reach a consensus on codes, categories, and themes.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Lung Cancer (Non-Small Cell)
Self-management Behavior
Physical Activity
Stress
Quality of Life
Resistance Training
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
Allocation Method
NA
Intervention Model
SINGLE_GROUP
Primary Study Purpose
SUPPORTIVE_CARE
Blinding Strategy
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Breathe Easier+
Breathe Easier+ includes guided instruction using a digital manual, a walking program, RT training sessions, a weekly telephone coaching call, daily text messages, and assessments at three time points.
Group Type
EXPERIMENTAL
Breathe Easier+
Intervention Type
BEHAVIORAL
Breathe Easier+ includes guided instruction using a digital manual, a walking program, RT training sessions, a weekly telephone coaching call, daily text messages, and assessments at three time points.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Breathe Easier+
Breathe Easier+ includes guided instruction using a digital manual, a walking program, RT training sessions, a weekly telephone coaching call, daily text messages, and assessments at three time points.
Intervention Type
BEHAVIORAL
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Survivors of NSCLC who have completed definitive treatment within the last 2 years.
* All participants must have a health clearance for physical activity signed by a healthcare provider; have Wi-Fi access; be able to provide informed consent; and be able to speak and read English.
* All participants must have a health clearance for physical activity signed by a healthcare provider; have Wi-Fi access; be able to provide informed consent; and be able to speak and read English.
Exclusion Criteria
* Survivors on current definitive treatment.
* All participants with a history of recurrent falls; a substantial mobility impairment related to chronic disease or injury; and lack of physical activity readiness as determined by a healthcare provider.
* All participants with a history of recurrent falls; a substantial mobility impairment related to chronic disease or injury; and lack of physical activity readiness as determined by a healthcare provider.
Minimum Eligible Age
21 Years
Eligible Sex
ALL
Accepts Healthy Volunteers
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of South Carolina
OTHER
Sponsor Role
lead
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Amanda Dyer
Assistant Professor
Responsibility Role
PRINCIPAL_INVESTIGATOR
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
University of South Carolina
Columbia, South Carolina, United States
Site Status
Countries
Review the countries where the study has at least one active or historical site.
United States
References
Explore related publications, articles, or registry entries linked to this study.
Lee EC, Whitehead AL, Jacques RM, Julious SA. The statistical interpretation of pilot trials: should significance thresholds be reconsidered? BMC Med Res Methodol. 2014 Mar 20;14:41. doi: 10.1186/1471-2288-14-41.
Reference Type
BACKGROUND
Beck SL, Schwartz AL, Towsley G, Dudley W, Barsevick A. Psychometric evaluation of the Pittsburgh Sleep Quality Index in cancer patients. J Pain Symptom Manage. 2004 Feb;27(2):140-8. doi: 10.1016/j.jpainsymman.2003.12.002.
Reference Type
BACKGROUND
Dorn LD, Lucke JF, Loucks TL, Berga SL. Salivary cortisol reflects serum cortisol: analysis of circadian profiles. Ann Clin Biochem. 2007 May;44(Pt 3):281-4. doi: 10.1258/000456307780480954.
Reference Type
BACKGROUND
Kim HG, Cheon EJ, Bai DS, Lee YH, Koo BH. Stress and Heart Rate Variability: A Meta-Analysis and Review of the Literature. Psychiatry Investig. 2018 Mar;15(3):235-245. doi: 10.30773/pi.2017.08.17. Epub 2018 Feb 28.
Reference Type
BACKGROUND
Tsiligianni IG, Alma HJ, de Jong C, Jelusic D, Wittmann M, Schuler M, Schultz K, Kollen BJ, van der Molen T, Kocks JW. Investigating sensitivity, specificity, and area under the curve of the Clinical COPD Questionnaire, COPD Assessment Test, and Modified Medical Research Council scale according to GOLD using St George's Respiratory Questionnaire cutoff 25 (and 20) as reference. Int J Chron Obstruct Pulmon Dis. 2016 May 18;11:1045-52. doi: 10.2147/COPD.S99793. eCollection 2016.
Reference Type
BACKGROUND
Ponce-Gonzalez JG, Sanchis-Moysi J, Gonzalez-Henriquez JJ, Arteaga-Ortiz R, Calbet JA, Dorado C. A reliable unipedal stance test for the assessment of balance using a force platform. J Sports Med Phys Fitness. 2014 Feb;54(1):108-17.
Reference Type
BACKGROUND
Melo TA, Duarte ACM, Bezerra TS, Franca F, Soares NS, Brito D. The Five Times Sit-to-Stand Test: safety and reliability with older intensive care unit patients at discharge. Rev Bras Ter Intensiva. 2019;31(1):27-33. doi: 10.5935/0103-507X.20190006. Epub 2019 Mar 14.
Reference Type
BACKGROUND
Chen MD, Kuo CC, Pellegrini CA, Hsu MJ. Accuracy of Wristband Activity Monitors during Ambulation and Activities. Med Sci Sports Exerc. 2016 Oct;48(10):1942-9. doi: 10.1249/MSS.0000000000000984.
Reference Type
BACKGROUND
Zimet GD, Powell SS, Farley GK, Werkman S, Berkoff KA. Psychometric characteristics of the Multidimensional Scale of Perceived Social Support. J Pers Assess. 1990 Winter;55(3-4):610-7. doi: 10.1080/00223891.1990.9674095.
Reference Type
BACKGROUND
Kim M, Yeom HE, Jung MS. Validation and psychometric properties of the multidimensional scale of perceived social support among Korean breast cancer survivors. Asia Pac J Oncol Nurs. 2022 Jan 30;9(4):229-235. doi: 10.1016/j.apjon.2022.01.004. eCollection 2022 Apr.
Reference Type
BACKGROUND
McDonnell KK, Gallerani DG, Newsome BR, Owens OL, Beer J, Myren-Bennett AR, Regan E, Hardin JW, Webb LA. A Prospective Pilot Study Evaluating Feasibility and Preliminary Effects of Breathe Easier: A Mindfulness-based Intervention for Survivors of Lung Cancer and Their Family Members (Dyads). Integr Cancer Ther. 2020 Jan-Dec;19:1534735420969829. doi: 10.1177/1534735420969829.
Reference Type
BACKGROUND
Cooley ME, Blonquist TM, Hong F, Nayak MM, Crouter SE, Hayman LL, Jaklitsch MT, Emmons KM, Bueno R. The effect of a lifestyle risk reduction intervention on lifestyle adherence and health-related quality of life in nonsmall cell lung cancer survivors: Feasibility study outcomes. Psychooncology. 2019 Apr;28(4):920-923. doi: 10.1002/pon.5002. Epub 2019 Feb 12. No abstract available.
Reference Type
BACKGROUND
Blok AC, Blonquist TM, Nayak MM, Somayaji D, Crouter SE, Hayman LL, Colson YL, Bueno R, Emmons KM, Cooley ME. Feasibility and acceptability of "healthy directions" a lifestyle intervention for adults with lung cancer. Psychooncology. 2018 Jan;27(1):250-257. doi: 10.1002/pon.4443. Epub 2017 May 31.
Reference Type
BACKGROUND
Heredia-Ciuro A, Martin-Nunez J, Lopez-Lopez JA, Lopez-Lopez L, Granados-Santiago M, Calvache-Mateo A, Valenza MC. Effectiveness of healthy lifestyle-based interventions in lung cancer survivors: a systematic review and meta-analysis. Support Care Cancer. 2022 Dec 21;31(1):71. doi: 10.1007/s00520-022-07542-0.
Reference Type
BACKGROUND
Campbell KL, Winters-Stone KM, Wiskemann J, May AM, Schwartz AL, Courneya KS, Zucker DS, Matthews CE, Ligibel JA, Gerber LH, Morris GS, Patel AV, Hue TF, Perna FM, Schmitz KH. Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable. Med Sci Sports Exerc. 2019 Nov;51(11):2375-2390. doi: 10.1249/MSS.0000000000002116.
Reference Type
BACKGROUND
Roddy MK, Flores RM, Burt B, Badr H. Lifestyle behaviors and intervention preferences of early-stage lung cancer survivors and their family caregivers. Support Care Cancer. 2021 Mar;29(3):1465-1475. doi: 10.1007/s00520-020-05632-5. Epub 2020 Jul 20.
Reference Type
BACKGROUND
Nightingale CL, Steffen LE, Tooze JA, Petty W, Danhauer SC, Badr H, Weaver KE. Lung Cancer Patient and Caregiver Health Vulnerabilities and Interest in Health Promotion Interventions: An Exploratory Study. Glob Adv Health Med. 2019 Jul 17;8:2164956119865160. doi: 10.1177/2164956119865160. eCollection 2019.
Reference Type
BACKGROUND
McDonnell KK, Owens OL, Hilfinger Messias DK, Heiney SP, Friedman DB, Campbell C, Webb LA. Health behavior changes in African American family members facing lung cancer: Tensions and compromises. Eur J Oncol Nurs. 2019 Feb;38:57-64. doi: 10.1016/j.ejon.2018.12.002. Epub 2018 Dec 7.
Reference Type
BACKGROUND
Cooley ME, Finn KT, Wang Q, Roper K, Morones S, Shi L, Litrownik D, Marcoux JP, Zaner K, Hayman LL. Health behaviors, readiness to change, and interest in health promotion programs among smokers with lung cancer and their family members: a pilot study. Cancer Nurs. 2013 Mar-Apr;36(2):145-54. doi: 10.1097/NCC.0b013e31825e4359.
Reference Type
BACKGROUND
Sande-Rivadulla M, Alonso-Calvete A, Soto-Gonzalez M. Effects of Muscle Strength Training in Prostate Cancer: A Systematic Review. Arch Esp Urol. 2024 Jan;77(1):1-15. doi: 10.56434/j.arch.esp.urol.20247701.1.
Reference Type
BACKGROUND
Chodosh J, Morton SC, Mojica W, Maglione M, Suttorp MJ, Hilton L, Rhodes S, Shekelle P. Meta-analysis: chronic disease self-management programs for older adults. Ann Intern Med. 2005 Sep 20;143(6):427-38. doi: 10.7326/0003-4819-143-6-200509200-00007.
Reference Type
BACKGROUND
Vijayvergia N, Shah PC, Denlinger CS. Survivorship in Non-Small Cell Lung Cancer: Challenges Faced and Steps Forward. J Natl Compr Canc Netw. 2015 Sep;13(9):1151-61. doi: 10.6004/jnccn.2015.0140.
Reference Type
BACKGROUND
Newsome BR, McDonnell K, Hucks J, Dawson Estrada R. Chronic Obstructive Pulmonary Disease: Clinical Implications for Patients With Lung Cancer. Clin J Oncol Nurs. 2018 Apr 1;22(2):184-192. doi: 10.1188/18.CJON.184-192.
Reference Type
BACKGROUND
Lowery AE, Krebs P, Coups EJ, Feinstein MB, Burkhalter JE, Park BJ, Ostroff JS. Impact of symptom burden in post-surgical non-small cell lung cancer survivors. Support Care Cancer. 2014 Jan;22(1):173-80. doi: 10.1007/s00520-013-1968-3. Epub 2013 Sep 10.
Reference Type
BACKGROUND
Granger CL, McDonald CF, Irving L, Clark RA, Gough K, Murnane A, Mileshkin L, Krishnasamy M, Denehy L. Low physical activity levels and functional decline in individuals with lung cancer. Lung Cancer. 2014 Feb;83(2):292-9. doi: 10.1016/j.lungcan.2013.11.014. Epub 2013 Nov 26.
Reference Type
BACKGROUND
Miller KD, Nogueira L, Devasia T, Mariotto AB, Yabroff KR, Jemal A, Kramer J, Siegel RL. Cancer treatment and survivorship statistics, 2022. CA Cancer J Clin. 2022 Sep;72(5):409-436. doi: 10.3322/caac.21731. Epub 2022 Jun 23.
Reference Type
BACKGROUND
McDonnell KK, Estrada RD, Dievendorf AC, Blew L, Sercy E, Khan S, Hardin JW, Warden D, Eberth JM. Lung cancer screening: Practice guidelines and insurance coverage are not enough. J Am Assoc Nurse Pract. 2019 Jan;31(1):33-45. doi: 10.1097/JXX.0000000000000096.
Reference Type
BACKGROUND
Related Links
Access external resources that provide additional context or updates about the study.
https://www.cancer.org/research/cancer-facts-statistics/all-cancer-facts-figures/2025-cancer-facts-figures.html
American Cancer Society. (2025). Cancer facts and figures 2025.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
Pro00144866
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.
Yoga in Improving Quality of Life in Patients With Non-small Cell Lung Cancer Undergoing Treatment
NCT02895503
TERMINATED
NA
A Series of Study in Testing Efficacy of Pulmonary Rehabilitation Interventions in Lung Cancer Survivors
NCT03918538
COMPLETED
NA
Self-Management Intervention for Breathlessness in Lung Cancer
NCT01585883
COMPLETED
NA
The Impact of Exercise on the Tumor Microenvironment in Patients With Lung Cancer
NCT07216209
NOT_YET_RECRUITING
NA
Effect of Exercise Therapy on Psychological State and Clinical Prognosis of Advanced Non-small Cell Lung Cancer
NCT05959265
UNKNOWN
NA
Physical Activity and Inactivity in Lung Cancer Survivors
NCT00582348
COMPLETED
Patient Function/Fitness and Psychosocial Health in Improving Health-Related Quality of Life in Patients With Stage I-IV Non-Small Cell Lung Cancer
NCT02835066
WITHDRAWN
A Feasibility Study of Unsupervised, Pre-operative Exercise Program for Patients Scheduled for Lung Cancer Surgery
NCT03162718
COMPLETED
NA
Improving Management of Breathlessness in Patients With Lung Cancer
NCT01937637
COMPLETED
NA
The Lived Experiences of Persons With Early Stage Non-small Cell Lung Cancer and Their Significant Other(s) Following Surgery: a Rapid Ethnographic Approach
NCT06536140
COMPLETED
Exercise Study in Patients With Lung Cancer
NCT01581346
COMPLETED
PHASE2
Resilience Measurement in Older Adults With Late-Stage Lung Cancer
NCT04825912
COMPLETED
NA
Engagement of Veterans With Lung Cancer
NCT07219251
NOT_YET_RECRUITING
NA
Exercise and Nutrition on Early-stage NSCLC Outcomes: the STARLighT Study
NCT07042724
RECRUITING
NA
Prospective, Longitudinal Biocollection in Thoracic Oncology, Including Newly Diagnosed Lung Cancer Patients
NCT06481813
RECRUITING
NA
Beneficial Effect of Pulmonary Rehabilitation in Lung Cancer Patients Receiving Radiation Therapy
NCT05414188
UNKNOWN
NA
Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer
NCT04067830
RECRUITING
PHASE2
Expiratory Muscle Strength Training in Improving Bulbar Function and Quality of Life in Patients With Head and Neck Cancer
NCT03175289
COMPLETED
NA
Effectiveness of Bronchoscopic Interventions for Malignant Airway Obstruction
NCT03326570
COMPLETED
Beyond the Lung Cancer Diagnosis: Leveraging the Oncology Clinic Setting for Actively Smoking Family Members
NCT03966807
TERMINATED
Exercise as Maintenance Therapy in Advanced Lung Cancer
NCT06513663
RECRUITING
NA
A Mobile SMART Exercise Support Program to Improve Fatigue in Lung Cancer Patients - A RCT
NCT05331391
UNKNOWN
NA
POSITIVE - Study (Part III) Heidelberg
NCT02055508
COMPLETED
NA
Supportive Care Mobile Application for Patients With NSCLC
NCT04629300
COMPLETED
NA