Shanghai Clinical Cohort - Adrenal Disease

NCT ID: NCT07191951

Last Updated: 2025-11-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

600 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-07-25

Study Completion Date

2025-12-31

Brief Summary

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As a vital organ responsible for producing life-sustaining hormones, the adrenal gland is associated with a wide range of diseases. These diseases affect multiple systems throughout the body and carry a high rate of mortality and disability. Current diagnosis and treatment face several challenges: significant variability in hormone testing results, inaccurate localization via imaging techniques, unclear molecular characteristics of adrenal tumors, and difficulty in determining prognosis through pathology. Therefore, establishing a clinical research cohort for adrenal diseases is essential. Such a cohort will enable in-depth exploration of disease mechanisms, identification of disease subtypes, optimization of diagnostic criteria, evaluation of treatment efficacy, advancement of personalized medicine, and formulation of prevention and treatment strategies.

Detailed Description

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Conditions

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Adrenal Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Adrenal cohort

Aged between 18 and 75 years; diagnosed with adrenal diseases, including primary aldosteronism, pheochromocytoma, Cushing's syndrome, congenital adrenal hyperplasia, adrenocortical carcinoma, etc.; in stable condition, capable of tolerating all examinations and follow-ups required by the study.

Receive adrenal surgery, radiotherapy, and/or medication therapy based on diagnosis and subtype classification.

Intervention Type OTHER

Receive adrenal surgery, radiotherapy, and/or medication therapy based on diagnosis and subtype classification.

Interventions

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Receive adrenal surgery, radiotherapy, and/or medication therapy based on diagnosis and subtype classification.

Receive adrenal surgery, radiotherapy, and/or medication therapy based on diagnosis and subtype classification.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* A signed and dated informed consent form
* Commitment to abide by the study procedures and cooperate with the implementation of the entire study process
* Patients diagnosed with adrenal diseases, including aldosteronism, Cushing's syndrome, pheochromocytoma, adrenocortical carcinoma, and congenital adrenal hyperplasia; regardless of whether they have received adrenal surgery, radiotherapy, and/or medication therapy
* Aged between 18 and 75 years

Exclusion Criteria

* Subjects meeting any of the following criteria will be excluded from this study:
* Refuse to sign the informed consent form
* Patients without adrenal diseases
* Have specified diseases or conditions (physical or psychological, identified through physical examination) that warrant exclusion from the study
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

UNKNOWN

Sponsor Role collaborator

RenJi Hospital

OTHER

Sponsor Role collaborator

Shanghai Zhongshan Hospital

OTHER

Sponsor Role collaborator

Shanghai Public Health Clinical Center

OTHER_GOV

Sponsor Role collaborator

Shanghai Jiao Tong University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Wang Weiqing

Director of the Department of Endocrinology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Jiang yiran

Shanghai, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Yiran Jiang

Role: CONTACT

0086-021-64370045

Facility Contacts

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Yiran Jiang

Role: primary

0086-021-64370045

Other Identifiers

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SHDC2025CCS022

Identifier Type: -

Identifier Source: org_study_id

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