The Risk of Adverse Pregnancy Outcomes for Long-term Exposure to Air Pollution in Pregnant Patients With Pulmonary Hypertension

NCT ID: NCT07164157

Last Updated: 2025-09-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-01-01

Study Completion Date

2022-12-31

Brief Summary

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With economic development and rapid urbanization, air pollution has become an increasingly severe public health concern. The risk of adverse pregnancy outcomes is significantly elevated for pregnant women complicated by pulmonary hypertension. However, no studies to date have specifically examined the impact of environmental factors on pulmonary hypertension in pregnant women, nor their subsequent birth outcomes. Therefore, investigating the correlation between them holds substantial clinical and public health significance.

Detailed Description

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The purpose of the research is preliminary found that the correlation between air pollution and maternal outcomes in pregnant women with pulmonary arterial hypertension and provide useful information for managment of pregnant women in special ambient conditions.

Conditions

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Pulmonary Arterial Hypertension Air Pollution Maternal Outcome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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The First Affiliated Hospital of Chongqing Medical University

No interventions assigned to this group

The Second Affiliated Hospital of Chongqing Medical University

No interventions assigned to this group

Xiangya Hospital of Central South University

No interventions assigned to this group

The second Xiangya Hospital of Central South University

No interventions assigned to this group

Yan'an Hospital of Kunming City

No interventions assigned to this group

Gansu Provincial Hospital

No interventions assigned to this group

Qilu Hospital of Shandong University

No interventions assigned to this group

The second hospital of Army Military University

No interventions assigned to this group

Guizhou Provincial People's Hospital

No interventions assigned to this group

The Second Affiliated Hospital of Nanchang University

No interventions assigned to this group

Henan Provincial People's Hospital

No interventions assigned to this group

Gannan Medical University

No interventions assigned to this group

Women and Children's Hospital of Chongqing Medical University

No interventions assigned to this group

The First People's Hosipital of Yunnan Province

No interventions assigned to this group

People's Hosipital of Xinjiang Uygur Autonomous Region

No interventions assigned to this group

The First Affiliated Hospital of Anhui Medical University

No interventions assigned to this group

Yantai Yuhuangding Hospital

No interventions assigned to this group

The Third People's Hosipital of Chengdu

No interventions assigned to this group

Zhongda Hospital Southeast University

No interventions assigned to this group

The First Affiliated Hospital of Xi'an Jiao Tong University

No interventions assigned to this group

Gansu Provincial Maternity and Child-care Hospital

No interventions assigned to this group

The First Affiliated Hospital of Guangxi Medical University

No interventions assigned to this group

Xijing Hospital

No interventions assigned to this group

Shenzhen People's Hospital

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Pregnant women with pulmonary hypertension who attended major medical centers included in this study from January 2013 to December 2022.

* Complete medical records available; ② Pulmonary artery systolic pressure ≥ 35 mmHg by echocardiography or a confirmed diagnosis of pulmonary hypertension by right heart catheterization; ③ Residential address information available at the city (district, county) level or higher.

Exclusion Criteria

* ① Unclear diagnosis and completely missing address information;

* Incomplete medical records; ③ Lost to follow-up during pregnancy or within six weeks postpartum.
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Wei Huang

OTHER

Sponsor Role lead

Responsible Party

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Wei Huang

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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The First Affiliated Hospital, Chongqing Medical University

Chongqing, Chongqing Municipality, China

Site Status

Countries

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China

Other Identifiers

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2025XMSB0000311

Identifier Type: -

Identifier Source: org_study_id

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