Effects of Multiple Interventions on Under-Five Diarrhea

NCT ID: NCT07158632

Last Updated: 2025-09-09

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 840 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-09-08
• Study Completion Date: 2025-12-24

Brief Summary

Diarrhea is the leading cause of death, especially in developed nations. Though there are effective interventions, diarrhea remains the leading cause of death among children in Ethiopia

Detailed Description

Diarrheal disease is the major cause of child morbidity and mortality in low-income countries, including Ethiopia. Diarrhea is more common in areas with a lack of water sanitation and hygiene. Even though there are available effective interventions, diarrhea remains the major cause of child morbidity and mortality in Ethiopia. Therefore, the aim of this study is to give up-to-date information on multiple interventions that reduce diarrheal disease.

Conditions

Diarrheal Diseases

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: FACTORIAL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: DOUBLE

Study Groups

handwashing education only arm

Arm A: This arm receives handwashing education.

Group Type: EXPERIMENTAL

handwashing education

Intervention Type: BEHAVIORAL

Arm A: This arm receive handwashing education using social and behavioral change communication

water chlorination only arm

Arm B: This arm receives household water chlorination

Group Type: EXPERIMENTAL

water chlorination

Intervention Type: BEHAVIORAL

Arm B: This arm receives water chlorination intervention

combined hand washing and water chlorination arm

Arm C: This arm receives both handwashing education and water chlorination.

Group Type: EXPERIMENTAL

combined intervention

Intervention Type: BEHAVIORAL

Arm C: This arm receives combined handwashing and water chlorination intervention

No intervention arm

This arm have not receive any intervention

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

handwashing education

Arm A: This arm receive handwashing education using social and behavioral change communication

Intervention Type: BEHAVIORAL

water chlorination

Arm B: This arm receives water chlorination intervention

Intervention Type: BEHAVIORAL

combined intervention

Arm C: This arm receives combined handwashing and water chlorination intervention

Intervention Type: BEHAVIORAL

Eligibility Criteria

Exclusion Criteria

• severely ill mother, households that receive treated water

• Minimum Eligible Age: 6 Months
• Maximum Eligible Age: 59 Months
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Jimma University

OTHER

Sponsor Role: lead

Responsible Party

Melaku Tesfaye

PhD Candidate

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Butajira Health Center

Butajīra, , Ethiopia

Countries

Ethiopia

Central Contacts

Melaku Tesfaye PhD Candidate, MPH

Role: CONTACT

tesfayemelaku96@gmail.com=

+251916141771

References

Breastfeeding and protection against diarrhea: an integrative review of literature Aleitamento materno e proteção contra diarreia: revisão integrativa da literatura Floriacy Stabnow Santos1 , Felipe César Stabnow Santos2 Adriana Moraes Leite1 , Leonardo Hunaldo dos Santos3 , Débora Falleiros de Mello1

Reference Type: BACKGROUND

Other Identifiers

JUIH/IRB/0509/25

Identifier Type: -

Identifier Source: org_study_id