Effect of Red and Blue Light Irradiation on Postoperative Wound Healing in Perianal Absces

NCT ID: NCT07155356

Last Updated: 2025-09-04

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 222 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-09-15
• Study Completion Date: 2026-09-30

Brief Summary

This study aims to investigate whether specialized red-blue light irradiation facilitates faster postoperative recovery and reduces complication rates in patients following perianal abscess surgery. A total of 222 eligible patients were randomly allocated equally into three groups (74 per group):①Routine Care Group: Standard wound care including cleansing and dressing changes；②Red Light Therapy Group: Routine care plus red light phototherapy；③Combined Red-Blue Light Therapy Group: Routine care plus concurrent red and blue light phototherapy.Wound healing time and incidence of complications were compared to assess postoperative recovery across interventions. The primary hypothesis posits that adjunctive phototherapy-particularly combined red-blue light irradiation-will significantly enhance wound healing, reduce edema and pain, and decrease complication rates (e.g.bleeding, urinary retention) compared to routine care alone.

Conditions

Perianal Abscess

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

control group

Routine care of patients after surgery for perianal abscesses.

Group Type: NO_INTERVENTION

No interventions assigned to this group

Red Ligh Group

Postoperative care of patients with perianal abscesses using routine plus red light irradiation.

Group Type: EXPERIMENTAL

Red light exposure

Intervention Type: DEVICE

Patients in the red light group received red light therapy concurrently with standard care.

Combined Red-Blue Light Group

Use of routine plus red and blue light in postoperative care of patients with perianal abscesses.

Group Type: EXPERIMENTAL

Red-blue light exposure

Intervention Type: DEVICE

Patients in the red and blue light group received combined red and blue light therapy concurrently with standard care。

Interventions

Red light exposure

Patients in the red light group received red light therapy concurrently with standard care.

Intervention Type: DEVICE

Red-blue light exposure

Patients in the red and blue light group received combined red and blue light therapy concurrently with standard care。

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• Aged between 18 and 75 years;
• Clinical diagnosis of perianal abscess；
• Procedure: Radical resection with incision and drainage.

Exclusion Criteria

• Concurrent anorectal disorders (hemorrhoids, anal fissure) or malignancies/infectious diseases；
• History of psychiatric disorders；
• Analgesic use within 7 days preoperatively；
• Coagulopathy or cardiac/hepatic dysfunction；
• Pregnancy or lactation；
• Contraindications to phototherapy；
• IBD-related perianal abscess.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

The Affiliated Hospital of Putian University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Affiliated Hospital of Putian University

Putian, , China

Countries

China

Central Contacts

Chenxing C Jian

Role: CONTACT

ptyyjcx@126.com

+8613959538950

Other Identifiers

AHPutianU-012

Identifier Type: -

Identifier Source: org_study_id