Comparative Study of Nutraceuticals vs. Conventional Prophylactic Therapy in the Management of Migraine
NCT ID: NCT07147972
Last Updated: 2025-08-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
PHASE3
100 participants
INTERVENTIONAL
2025-08-20
2026-02-01
Brief Summary
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Detailed Description
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\- To compare the reduction in the frequency of migraine attacks between patients receiving conventional prophylactic therapy and those receiving a nutraceutical combination.
Secondary Objectives:
* To evaluate changes in migraine intensity (VAS score), duration, and MIDAS score.
* To assess the side effect profile and patient satisfaction with both interventions.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Group 1
Conventional Therapy
Propranolol 80 mg
Propranolol 40-80 mg/day
Group 2
Nutraceutical Therapy
Magnesium 400Mg
Magnesium 400 mg daily
Interventions
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Propranolol 80 mg
Propranolol 40-80 mg/day
Magnesium 400Mg
Magnesium 400 mg daily
Eligibility Criteria
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Inclusion Criteria
* \- Diagnosed with episodic migraine (ICHD-3 criteria)
* \- ≥4 migraine attacks/month for the past 3 months
* \- Willing to provide informed consent
Exclusion Criteria
* \- Use of other prophylactic treatments in past month
* \- History of secondary headaches
* \- Pregnancy or breastfeeding
* \- Significant renal, hepatic, or cardiac disease
18 Years
ALL
No
Sponsors
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Fayoum University
OTHER
Responsible Party
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Marwa Ahmed Kamal Tolba
Associate professor clinical pharmacy department -faculty of pharmacy- fayoum university
Central Contacts
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References
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Charles A. The pathophysiology of migraine: implications for clinical management. Lancet Neurol. 2018 Feb;17(2):174-182. doi: 10.1016/S1474-4422(17)30435-0. Epub 2017 Dec 8.
Other Identifiers
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Management of Migraine
Identifier Type: -
Identifier Source: org_study_id
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