Vitamin K Antagonist in Rheumatic Heart Disease Patients With Mechanical Heart Valves: Our Current Status
NCT ID: NCT07146282
Last Updated: 2025-08-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
165 participants
OBSERVATIONAL
2025-09-30
2027-10-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
CROSS_SECTIONAL
Eligibility Criteria
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Inclusion Criteria
* Aged ≥18 years
Exclusion Criteria
* Active bleeding disorders.
* Severe liver/kidney disease (if affecting anticoagulation).
18 Years
ALL
No
Sponsors
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Ahmed Hassan Rostom Ibrahim
OTHER
Responsible Party
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Ahmed Hassan Rostom Ibrahim
principal investigator
Principal Investigators
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Hamdy Shams Mohamed
Role: PRINCIPAL_INVESTIGATOR
Tarek hameed Nageeb
Role: PRINCIPAL_INVESTIGATOR
Central Contacts
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References
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Watkins DA, Johnson CO, Colquhoun SM, Karthikeyan G, Beaton A, Bukhman G, Forouzanfar MH, Longenecker CT, Mayosi BM, Mensah GA, Nascimento BR, Ribeiro ALP, Sable CA, Steer AC, Naghavi M, Mokdad AH, Murray CJL, Vos T, Carapetis JR, Roth GA. Global, Regional, and National Burden of Rheumatic Heart Disease, 1990-2015. N Engl J Med. 2017 Aug 24;377(8):713-722. doi: 10.1056/NEJMoa1603693.
Beckmann A, Meyer R, Lewandowski J, Markewitz A, Blassfeld D, Boning A. German Heart Surgery Report 2022: The Annual Updated Registry of the German Society for Thoracic and Cardiovascular Surgery. Thorac Cardiovasc Surg. 2023 Aug;71(5):340-355. doi: 10.1055/s-0043-1769597. Epub 2023 Jun 16.
El-Hamamsy I, Toyoda N, Itagaki S, Stelzer P, Varghese R, Williams EE, Erogova N, Adams DH. Propensity-Matched Comparison of the Ross Procedure and Prosthetic Aortic Valve Replacement in Adults. J Am Coll Cardiol. 2022 Mar 1;79(8):805-815. doi: 10.1016/j.jacc.2021.11.057.
Zilla P, Human P, Pennel T. Mechanical valve replacement for patients with rheumatic heart disease: the reality of INR control in Africa and beyond. Front Cardiovasc Med. 2024 Feb 9;11:1347838. doi: 10.3389/fcvm.2024.1347838. eCollection 2024.
Related Links
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Related Info
Other Identifiers
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VKA in RHD current status
Identifier Type: -
Identifier Source: org_study_id
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