Evaluation of Efficacy of Neem (Azadirachta Indica) Versus Triamcinolone Acetonide in the Treatment of Oral Lichen Planus.
NCT ID: NCT07141446
Last Updated: 2025-09-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1/PHASE2
60 participants
INTERVENTIONAL
2023-02-05
2024-02-28
Brief Summary
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To compare the efficacy of 1.5% Neem Gel (Azadirachta Indica) versus 0.1% Triamcinolone Acetonide in treatment of Oral Lichen Planus (OLP) as a topical treatment modality for patients with OLP,
Researchers will compare Neem to a corticosteroid (a standard treatment for Oral Lichen Planus) to see if Neem works to treat Oral Lichen Planus.
Participants:
In experimental group were given Neem Gel in Orabase formulations and control group with topical Triamcinolone acetonide oral paste to be used twice every day for 3 months Visit the clinic once every month for checkups.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Neem
Neem gel
1.5% Neem Gel in orabase formulation, twice daily application for 3 months
Triamcinolone Acetonide
Triamcinolone Acetonide
0.1% oral paste to be applied twice daily for 3 months
Interventions
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Neem gel
1.5% Neem Gel in orabase formulation, twice daily application for 3 months
Triamcinolone Acetonide
0.1% oral paste to be applied twice daily for 3 months
Eligibility Criteria
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Inclusion Criteria
* Patient above 20 years of age.
* Patient willing to participate in the study with informed consent.
* Patient with recalcitrant OLP.
Exclusion Criteria
* Patients with lichenoid lesions.
* Patients with associated cutaneous lesions.
* Pregnant or lactating females.
20 Years
85 Years
ALL
No
Sponsors
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Goa Dental College
OTHER_GOV
Responsible Party
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Medhana Mangaonker
Principal Investigator
Locations
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Department of Oral Medicine and radiology, Goa Dental College and Hospital, Bambolim Goa India
Goa, Bambolim, India
Countries
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Other Identifiers
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GDCH/IEC/I-2024(04)
Identifier Type: -
Identifier Source: org_study_id
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