Thyme Honey for Management of Oral Lichen Planus

NCT ID: NCT06810752

Last Updated: 2025-02-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Clinical Phase

PHASE1/PHASE2

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-10-12

Study Completion Date

2025-03-31

Brief Summary

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the study aimed to assess the effect of topical application of thyme honey in comparison to 0.1% triamcinolone acetonide oral paste on the relief of pain and clinical improvement in patients with OLP

Detailed Description

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Conditions

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Oral Lichen Planus

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Thyme Honey group

Topical application of Thyme Honey

Group Type ACTIVE_COMPARATOR

thyme honey

Intervention Type DIETARY_SUPPLEMENT

Topical application on the oral mucosa

Control group

Topical application of Triamcinolone acetonide

Group Type PLACEBO_COMPARATOR

Triamcinolone Acetonide

Intervention Type DRUG

Topical application on the oral mucosa

Interventions

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thyme honey

Topical application on the oral mucosa

Intervention Type DIETARY_SUPPLEMENT

Triamcinolone Acetonide

Topical application on the oral mucosa

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients free from any visible oral lesions other than OLP.
* Patients who agreed to take supplied medications.
* Patients who agreed for the biopsy (when required).

Exclusion Criteria

* Treatment with any systemic treatment such as systemic steroids, other immunosuppressive drugs or non-steroidal anti-inflammatory drugs at least eight weeks.
* Treatment with any oral topical medications for at least four weeks prior to the study.
* Pregnant and lactating women.
* In addition, no consideration was given to patients with a history of hypersensitivity to honey.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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British University In Egypt

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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The British university in Egypt

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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24-092

Identifier Type: -

Identifier Source: org_study_id

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