The Efficacy of Topical Sesame Oil Versus Topical Triamcinolone on Oral Lichen Planus and Salivary Level of Oxidative Stress Biomarker [MDA]
NCT ID: NCT03738176
Last Updated: 2019-08-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
EARLY_PHASE1
40 participants
INTERVENTIONAL
2019-12-16
2020-12-30
Brief Summary
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Detailed Description
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* Test group will receive topical sesame oil (3 times /day after eating) for a month.
* Control group will receive topical corticosteroid (3 times /day after eating) for a month.
* Assessment of the appearance score and severity of pain as well as the clinical parameter outcome will be done at baseline and at the end of two and four weeks and will be recorded in the patients' questionnaires \& by clinical sign score . MDA will be measured at the baseline \& at the end of four weeks after treatment.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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sesame oil in orabase
20 gm sesame oil-80 gm CMC 3 times per day for one month
Sesame Oil
Sesame oil(80 gm NaCMC-20 gmSesame oil)
triamcinolone in orabase
140 gm triamcinolone-50 gm Na CMC 3 times per day for one month
triamcinolone in orabase
triamcinolone 140 gm-Na CMC 50 gm
Interventions
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Sesame Oil
Sesame oil(80 gm NaCMC-20 gmSesame oil)
triamcinolone in orabase
triamcinolone 140 gm-Na CMC 50 gm
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Patients with no history of taking topical corticosteroids for the last 2 months and systemic corticosteroid for the last 6 months
* Patients who agree to take medication and follow up .
Exclusion Criteria
* Patients with history of topical steroids during last 2 months \& systemic steroids during last 6 months.
* Patients with recent dental filling associated with the lesion or associated with recent drug administration.
* Patient with history of diabetes or hypertension or those with positive HCV ab or HBs Ag.
18 Years
80 Years
ALL
No
Sponsors
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Mona Taha Mohammed MD
OTHER
Responsible Party
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Mona Taha Mohammed MD
clinical researcher
Principal Investigators
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Mona Taha Mohammed Ahammed, MD
Role: PRINCIPAL_INVESTIGATOR
Cairo U
Central Contacts
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Other Identifiers
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2:5:1
Identifier Type: -
Identifier Source: org_study_id
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