High-Frequency QRS for Predicting Microvascular Dysfunction and Adverse Events After PCI in Acute Myocardial Infarction
NCT ID: NCT07138638
Last Updated: 2025-08-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
1112 participants
OBSERVATIONAL
2025-08-31
2027-12-31
Brief Summary
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1. Whether HF-QRS could serve as an effective tool for early identification of high-risk AMI patients and prognosis prediction;
2. Whether HF-QRS provides auxiliary diagnostic value for post-AMI microvascular dysfunction.
Participants underwent HF-QRS assessment and were prospectively followed for 1 year to record the incidence of major adverse cardiovascular events (MACE).
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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High-Frequency QRS
All enrolled patients underwent HF-QRS assessment, with subsequent recording of MACE to evaluate the predictive value of HF-QRS parameters for clinical outcomes
Eligibility Criteria
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Inclusion Criteria
Diagnosed with acute myocardial infarction (AMI, including STEMI and NSTEMI) and underwent successful emergency PCI
Voluntarily participated and provided written informed consent
Exclusion Criteria
QRS duration \>120 ms (including paced rhythm, WPW syndrome, bundle branch block, or left ventricular hypertrophy with repolarization abnormalities)
Structural heart disease (congenital heart disease, cardiomyopathy, aortic dissection, etc.)
Persistent atrial fibrillation or malignant arrhythmias
History of cerebral hemorrhage or ischemic stroke within 1 month
Prolonged cardiopulmonary resuscitation or requiring advanced life support (IABP/ECMO, etc.)
Scheduled for imminent surgery with anticipated inability to complete HF-QRS assessment
Other life-threatening conditions including: Severe hepatic or renal dysfunction;Uncontrolled systemic diseases;Hematologic disorders;Active infections;Malignancy with life expectancy \<1 year Other investigator-determined exclusionary conditions:Pregnancy;Concurrent participation in other clinical trials
Refusal to participate in the clinical study
18 Years
75 Years
ALL
No
Sponsors
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The Affiliated Hospital of Xuzhou Medical University
OTHER
Responsible Party
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Principal Investigators
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Yong Huo, Ph.D
Role: STUDY_CHAIR
Department of Cardiology, Peking University First Hospital, Beijing, China
Yuan Lu, Ph.D
Role: STUDY_DIRECTOR
The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221002
Locations
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The Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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XYFY2025-KL303-01
Identifier Type: -
Identifier Source: org_study_id
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