Hyperbaric Oxygen Therapy Used on Severely Injured Healthy Individuals With Fungal Infections

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

7 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-08-04

Study Completion Date

2025-12-31

Brief Summary

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The goal of this observational study is to learn about the effects of Hyperbaric Oxygen Therapy on healthy individual who suffer from invasive fungal infection caused by severe trauma, who do not respond to conventional treatment. The main question it aims to answer is:

Does the treatment aid in eradicating the infection and improve the overall outcome of such patients?

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Detailed Description

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Conditions

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Invasive Fungal Infections Hyperbaric Oxygen Therapy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Hyperbaric Oxygen Therapy

Intervention Type OTHER

Hyperbaric Oxygen Therapy at increasing pressure to 2.8 ATA for 2 hours sessions. Breaks of 5 every 20 minutes from the oxygen to air to avoid hyperoxia. Continued for the duration of the hospitalization in the ICU on a daily basis.

Interventions

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Hyperbaric Oxygen Therapy

Hyperbaric Oxygen Therapy at increasing pressure to 2.8 ATA for 2 hours sessions. Breaks of 5 every 20 minutes from the oxygen to air to avoid hyperoxia. Continued for the duration of the hospitalization in the ICU on a daily basis.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* at least 18 year old
* Trauma as the insult type causing the infection
* Refractory IFI with failure to respond to standard therapy (medical and surgical)
* Hyperbaric Oxygen Therapy as part of the treatment