EEG Measurements to Capture DBS-induced Electric Potentials

NCT ID: NCT07115394

Last Updated: 2025-08-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-07-11

Study Completion Date

2026-12-31

Brief Summary

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To measure the electric fields induced by DBS (deep brain stimulation) on the scalp and to improve electric field simulations, the investigators will measure EEG (electroencephalography) measurements with high sampling rates (\>100 kHz). The investigators hypothesize that we can improve electric field simulations of DBS by validating and calibrating the simulations based on EEG measurements at high sampling rates (\>100 kHz).

Detailed Description

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Conditions

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Deep Brain Stimulation Parkinson's Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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EEG measurement during DBS

Different DBS conditions can include the individual bilateral therapeutical DBS settings, unilateral versions of these setting, unilateral single segment use of these settings or unilateral low frequency (15-30 Hz) DBS. EEG measurements with a 4-channel analog EEG amplifier (Digitimer EEG).

EEG recording

Intervention Type OTHER

EEG will be recorded at high sampling rate

Interventions

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EEG recording

EEG will be recorded at high sampling rate

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Provision of written informed consent by the patient
* Age 35 - 85
* patient groups: Parkinson's disease, essential tremor, dystonia
* \>3 months after surgery for DBS

Exclusion Criteria

none.
Minimum Eligible Age

35 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Twente

OTHER

Sponsor Role collaborator

Universitätsklinikum Hamburg-Eppendorf

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University Medical Center Hamburg-Eppendorf

Hamburg, , Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Bettina C. Schwab, PhD

Role: CONTACT

+49 40 7410 26907

Thomas Keizers

Role: CONTACT

Facility Contacts

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Monika Pötter-Nerger, PhD

Role: primary

+49 (0) 40 7410 - 50134

Other Identifiers

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101116047

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

2023-101217-BO-ff_1

Identifier Type: -

Identifier Source: org_study_id

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