Intra Cranial EEG Activity During Dexmedetomidine Sedation

NCT ID: NCT01648959

Last Updated: 2022-12-22

Basic Information

• Recruitment Status: TERMINATED
• Total Enrollment: 5 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2012-07-31
• Study Completion Date: 2014-03-31

Brief Summary

Various parts of the brain are sensitive to various anesthetics.We like to study the effect of dexmedetomidine on the different parts of the brain in patients who are coming for DBS electrode removal under sedation.

Detailed Description

Cortical and sub cortical structures will have different sensitivities to various anesthetics.The objective of this study is to look at the changes in the intracranial electroencephalographic (EEG) characteristics during dexmedetomidine sedation and to determine the differences in the EEG characteristics between cortical and subcortical structures.

Conditions

Complex Partial Seizures

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Interventions

EEG Recording

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Adults between 18 to 80 years of age, who are scheduled for elective removal of intracranial (surface and depth) electrodes under conscious sedation

Exclusion Criteria

• Lack of informed consent
• Hypersensitivity to dexmedetomidine
• Language barrier
• Emergency surgery

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Health Network, Toronto

OTHER

Sponsor Role: lead

Responsible Party

Lashmi Venkatraghavan

Dr.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

lashmikumar venkatraghavan, MD

Role: PRINCIPAL_INVESTIGATOR

Assistant professor,Toronto western hospital,university health network (UHN)

Locations

Toronto Western Hospital,UHN.

Toronto, Ontario, Canada

Countries

Canada

Other Identifiers

12-0268

Identifier Type: -

Identifier Source: org_study_id