Results of Laparoscopic Appendectomy With Application of Clips Versus Ligature for Stump Closure

NCT ID: NCT07115303

Last Updated: 2025-08-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-07-14

Study Completion Date

2026-02-28

Brief Summary

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This a prospective study to compare between clipping and ligation of appendicular stump in laparoscopic appendectomies regarding ;technical feasibility , post operative complications as fecal fistula and economic consideration.

Detailed Description

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Conditions

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Appendicitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Laparoscopic Appendectomy with application of clips for stump closure

Group Type ACTIVE_COMPARATOR

Laparoscopic Appendectomy with application of clips for stump closure

Intervention Type PROCEDURE

in patients who will undergo Laparoscopic Appendectomy, appendicular stump will be closed by application of clips

Laparoscopic Appendectomy with ligature for stump closure

Group Type ACTIVE_COMPARATOR

Laparoscopic Appendectomy with ligature for stump closure

Intervention Type PROCEDURE

in patients who will undergo Laparoscopic Appendectomy, appendicular stump will be closed by ligation

Interventions

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Laparoscopic Appendectomy with application of clips for stump closure

in patients who will undergo Laparoscopic Appendectomy, appendicular stump will be closed by application of clips

Intervention Type PROCEDURE

Laparoscopic Appendectomy with ligature for stump closure

in patients who will undergo Laparoscopic Appendectomy, appendicular stump will be closed by ligation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Any patient diagnosed with acute appendicitis of any age and of any sex presented to ER of the Department of General, Laparoscopic and Oncologic Surgery Department, Sohag University Hospital will be enrolled in this study.

Exclusion Criteria

* Patients with complicated appendicitis.
* Patients with unstable cardiac or pulmonary condition.
* Patients with suspicious crhon's disease or mass intraoperative.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Ahmed Amer Abdelraheem

Resident of General, Oncologic& Laparscopic Surgery Faculty of Medicine, Sohag University

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sohag university hospital

Sohag, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Ahmed A Abdelreheem, Resident

Role: CONTACT

01026675749

Mohamed M Ali, Professor

Role: CONTACT

01004564240

Facility Contacts

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magdy M Amin, professor

Role: primary

References

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Makaram N, Knight SR, Ibrahim A, Patil P, Wilson MSJ. Closure of the appendiceal stump in laparoscopic appendectomy: A systematic review of the literature. Ann Med Surg (Lond). 2020 Aug 4;57:228-235. doi: 10.1016/j.amsu.2020.07.058. eCollection 2020 Sep.

Reference Type BACKGROUND
PMID: 32802324 (View on PubMed)

Farahani PK, Safaei N. Comparison of two methods: Clipping and suturing in laparoscopic appendectomy. Surg Open Sci. 2024 May 3;19:162-165. doi: 10.1016/j.sopen.2024.04.007. eCollection 2024 Jun.

Reference Type BACKGROUND
PMID: 38764557 (View on PubMed)

Poon SHT, Law SY, Lai ATY. Clips closure versus endoloop ligation in laparoscopic appendectomy: a systematic review and meta-analysis of comparative studies. Ann Med Surg (Lond). 2023 Sep 6;85(10):5011-5021. doi: 10.1097/MS9.0000000000001260. eCollection 2023 Oct.

Reference Type BACKGROUND
PMID: 37811063 (View on PubMed)

Other Identifiers

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Soh-Med-25-7---18MS

Identifier Type: -

Identifier Source: org_study_id

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