Laparoscopic Clipping Versus Extracorporeal Ligation in Complicated Appendicitis Upper Egypt Overview
NCT ID: NCT05637554
Last Updated: 2023-02-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
40 participants
INTERVENTIONAL
2023-02-28
2024-01-31
Brief Summary
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Detailed Description
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There are many methods for securing the base of the appendix, some of which are expensive others are not available or technically demanding. In this study the investigators aim to compare between extracorporeal ligation and clipping techniques regarding feasibility, safety, efficacy, operative time, postoperative outcome and complications especially in complicated appendicitis.
AS management of complicated appendicitis laparoscopically is possible, secure and can lead to a little occurrence of infectious complications, fewer post-operative pain, quick revival and improve cosmesis so the investigators will do a prospective clinical trial comparative study between two common techniques to determine the best one in management of complicated cases.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Laparoscopic clipping appendectomy
This group will undergo laparoscopic clipping of the base of the appendix during laparoscopic appendectomy.
Laparoscopic appendectomy using clipping.
Laparoscopic appendectomy using clipping to secure the base of the appendix.
Laparoscopic extracorporeal ligation appendectomy
This group will undergo laparoscopic extracorporeal ligation of the base of the appendix during laparoscopic appendectomy.
Laparoscopic appendectomy using extracorporeal ligation to secure the base of the appendix.
Laparoscopic appendectomy using extracorporeal ligation to secure the base of the appendix.
Interventions
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Laparoscopic appendectomy using clipping.
Laparoscopic appendectomy using clipping to secure the base of the appendix.
Laparoscopic appendectomy using extracorporeal ligation to secure the base of the appendix.
Laparoscopic appendectomy using extracorporeal ligation to secure the base of the appendix.
Eligibility Criteria
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Inclusion Criteria
* Perforated appendicitis (diagnosed intraoperatively)
* Patients who will undergo laparoscopic appendectomy.
Exclusion Criteria
* Patients who are not fit for laparoscopic appendectomy.
7 Years
60 Years
ALL
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Mohamed Ahmed Hamed Mohamed Elfoly
Resident Doctor
Principal Investigators
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Hisham Ali Riad Shaban, Professor
Role: PRINCIPAL_INVESTIGATOR
Assiut University
Moustafa Mahmoud Ebrahem
Role: PRINCIPAL_INVESTIGATOR
Assiut University
Moustafa Ali Sayed Mahmoud
Role: PRINCIPAL_INVESTIGATOR
Assiut University
Central Contacts
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References
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Bessoff KE, Choi J, Wolff CJ, Kashikar A, Carlos GM, Caddell L, Khan RI, Stave CD, Spain DA, Forrester JD. Evidence-based surgery for laparoscopic appendectomy: A stepwise systematic review. Surg Open Sci. 2021 Aug 26;6:29-39. doi: 10.1016/j.sopen.2021.08.001. eCollection 2021 Oct.
Casas MA, Dreifuss NH, Schlottmann F. High-volume center analysis and systematic review of stump appendicitis: solving the pending issue. Eur J Trauma Emerg Surg. 2022 Jun;48(3):1663-1672. doi: 10.1007/s00068-021-01707-y. Epub 2021 Jun 3.
Mannu GS, Sudul MK, Bettencourt-Silva JH, Cumber E, Li F, Clark AB, Loke YK. Closure methods of the appendix stump for complications during laparoscopic appendectomy. Cochrane Database Syst Rev. 2017 Nov 13;11(11):CD006437. doi: 10.1002/14651858.CD006437.pub3.
Delibegovic S, Mehmedovic Z. The influence of the different forms of appendix base closure on patient outcome in laparoscopic appendectomy: a randomized trial. Surg Endosc. 2018 May;32(5):2295-2299. doi: 10.1007/s00464-017-5924-z. Epub 2017 Nov 2.
Other Identifiers
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Laparoscopic appendectomy.
Identifier Type: -
Identifier Source: org_study_id
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