Laparoscopic Versus Open Surgical Repair of Genitovesical Fistula in Females
NCT ID: NCT07043062
Last Updated: 2025-06-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
50 participants
INTERVENTIONAL
2024-08-01
2025-08-01
Brief Summary
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Genitourinary fistula refers to a fistula that occurs between reproductive tract organs (vagina, cervix, and uterus), and lower urinary tract (bladder, urethra, and pelvic ureters).
It is a serious condition which can significantly influence the biological and psychological condition of women, with a negative impact on the quality of life.
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Detailed Description
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Genitourinary fistula refers to a fistula that occurs between reproductive tract organs (vagina, cervix, and uterus), and lower urinary tract (bladder, urethra, and pelvic ureters).
It is a serious condition which can significantly influence the biological and psychological condition of women, with a negative impact on the quality of life.
In developed countries, iatrogenic injury during hysterectomy or pelvic surgery is the primary cause of fistulae . However, the etiology differs in developing countries, being secondary to prolonged, obstructed, complicated labor.
Genitovesical fistulae are one of the most devastating complications in the urogynecology setting. The commonest type of these fistulae is the vesicovaginal fistula (VVF);the patients Suffering from continuous urinary leakage through the vagina and urinary smell, patients with VVF face hygienic, social, infectious, psychological, and sexual problems.
Vesicouterine fistulae (VUF) are not as common as VVF. In 1908, the first case was reported by Knipe , and later in 1957, Youssef reported on the classic symptoms of VUF. These symptoms included amenorrhea and cyclic hematuria, or menouria; known afterward as Youssef's syndrome. The prevalence of these fistulae is estimated to be 1-4% of all genitourinary fistulae.
Several options for the management of such fistulae have been discussed; these include conservative treatment with prolonged catheterization , open surgery, cysto-fulguration, endourology, and laparoscopy/robotic surgery. The decision-making is guided by the patient characteristics, etiology, and the experience of the treating surgeon.
Laparoscopy is of great advantage when compared to open surgery, including safe, effective, minimally invasive procedure, less postoperative pain, smaller incisions, lower blood loss, a shorter hospital stay, and faster recovery. It is associated with a lower incidence of postoperative complications, including infections and improper wound healing
Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Group of Laparoscopic Repair
About 25 female patients suffering from Vesicovaginal fistula or Vesicouterine fistula and will be subjected to Laparoscopic repair of the fistula
Open surgical Interference
to compare the outcomes of Laparoscopic repair versus Open surgical repair of Genitovesical fistula in females.
Group of Open Surgical Repair
About 25 female patients suffering from Vesicovaginal fistula or Vesicouterine fistula and will be subjected to surgical repair of the fistula.
Open surgical Interference
to compare the outcomes of Laparoscopic repair versus Open surgical repair of Genitovesical fistula in females.
Interventions
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Open surgical Interference
to compare the outcomes of Laparoscopic repair versus Open surgical repair of Genitovesical fistula in females.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Timing of repair after 2-6 months of beginning of symptoms and signs of fistula.
Exclusion Criteria
* Females with congenital disease in Bladder ,Uterus or Vagina.
* Females with Vaginal or Uterine prolapse.
25 Years
70 Years
FEMALE
No
Sponsors
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South Valley University
OTHER
Responsible Party
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Hassan Elshazly Khodary
Resident at Urology Department, Faculty of Medicine
Principal Investigators
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Ahmed Aboalyosr Mohamed, Professor
Role: STUDY_CHAIR
Urology Department, Faculty of Medicine, South Valley University, Qena, Egypt
Locations
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South Valley University Hospital
Qina, , Egypt
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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Female Genitovesical fistula
Identifier Type: -
Identifier Source: org_study_id
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