EFFECT OF ELECTROACUPUNCTURE ON COMPLEX REGIONAL PAIN SYNDROME IN PATIENTS WITH STROKE: A RANDOMIZED CONTROLLED TRIAL

NCT ID: NCT07091708

Last Updated: 2025-07-29

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 40 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-08-15
• Study Completion Date: 2026-06-15

Brief Summary

Complex regional pain syndrome (CRPS) is a condition marked by pain that may occur spontaneously or in response to stimuli, often disproportionate to the initial injury.(Chae, 2010). In post-stroke complex regional pain syndrome, patients often have simultaneous shoulder and wrist pain. Symptoms may include edema, increased warmth in the hand, and limited in upper extremity joints. (Yu, 2009).The significance of post-stroke complex regional pain syndrome (CRPS) lies not only in its profound impact on pain perception but also in its broader effects on patients' quality of life.(de mos et al.,2007) Managing complex regional pain syndrome involves a multidisciplinary approach with key physical therapy elements like elevation, massage, range of motion exercises, strengthening, and sensory re-education.(Sethy et al., 2017). Electrotherapy modalities include transcutaneous electrical nerve stimulation. (Palmer, 2015). This includes heat treatments like ultrasound, hot and cold packs, and fluidotherapy

Detailed Description

In this sense,acupuncture, presents a viable alternative to opioid analgesics for pain relief, offering effective treatment without the risk of dependency. one specific technique, electroacupuncture (ea), enhances traditional acupuncture by applying a small electric current between pairs of needles. research indicates that ea may alleviate pain by activating various bioactive chemicals, engaging multiple mechanisms at the peripheral, spinal, and supraspinal levels. this makes electroacupuncture a promising option for individuals seeking non-addictive pain management solutions.( zhang r, et al 2014).

Conditions

Stroke

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

intervention

Group Type: OTHER

Acupuncture

Intervention Type: OTHER

Acupuncture

Interventions

Acupuncture

Acupuncture

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• 1. The study involved forty patients male and female aged between 45 and 65 years. 2. A confirmed diagnosis of complex regional pain syndrome through clinical assessment by neurologist using The Budapest criteria for diagnosis of CRPS (Choi et al ., 2013

Exclusion Criteria

• 1. Pre-existing history of hand problems and shoulder dysfunction prior to experiencing a stroke . 2. Those with an overactive sympathetic system from alternative causes eg.congestive heart failure,chronic kidney disease(Reynolds & Minic, 2023) 8 3. individuals with significant musculoskeletal disorders such as rheumatoid arthritis or metabolic disorders including diabetes 4. Pregnancy

• Minimum Eligible Age: 45 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Cairo University

OTHER

Sponsor Role: lead

Responsible Party

Eyad Mohamed Fathy

Demonstator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

1534998

Identifier Type: -

Identifier Source: org_study_id