Virtual Reality in Intensive Care Unit: Patient Satisfaction, Clinical and Functional Outcomes, Feasibility

NCT ID: NCT07089134

Last Updated: 2025-09-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-12-15

Study Completion Date

2026-08-31

Brief Summary

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Background: Virtual reality is recognized as a progressive technology with the potential to enhance the rehabilitation process. Immersive virtual reality-based treatments can improve motor outcomes in physical rehabilitation, reduce stress caused by the intensive care unit environment and maximize patients' recovery processes.

Objective: To analyze the efficacy of rehabilitation using immersive virtual reality on patient satisfaction and experience, functional and clinical outcomes and the feasibility of its application during the hospitalization period in an intensive care unit (ICU).

Methods: This is a randomized controlled clinical trial involving ICU patients aged 18 years or older, with an estimated ICU stay of ≥ 72 hours, the ability to understand and follow verbal instructions and no diagnosis of psychotic disorders, visual impairment, or hearing loss. Patients will be divided into two groups: one undergoing traditional physiotherapy rehabilitation - control group (CG), and the other receiving physiotherapy using immersive virtual reality (IVR group). The following evaluations will be conducted: mobility condition, physical and psychological discomfort, estimated physical activity level, occurrence of delirium, cognitive decline screening, functionality classification, motivation level, patient experience, sense of immersion in the virtual reality environment, patient satisfaction during the rehabilitation process, occurrence of adverse events, and protocol feasibility. Data will be presented in graphs and tables. Results will be considered statistically significant at a 5% significance level (p ≤ 0.05), and all analyses will be performed using SPSS Statistics version 22.

Expected results: The investigators expect to find evidence that rehabilitation using immersive virtual reality can promote and enable a more pleasant and less traumatic experience during the patient's hospitalization, with greater satisfaction and adherence to the proposed rehabilitation, in addition to being an effective tool to optimize patients' functional and clinical outcomes.

Detailed Description

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Conditions

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Hospitalized Patients ICU Hospitalization Intensive Care Unit-acquired Weakness

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Considering that patients enrolled in the study must complete a total of 6 to 14 rehabilitation protocol sessions, and in order to ensure the accuracy of the outcomes analyzed, participants who are absent for more than two consecutive rehabilitation sessions or who do not complete at least 70% of the total number of sessions will be excluded from the final analysis of the study.
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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traditional physiotherapy rehabilitation

The traditional physiotherapeutic rehabilitation protocol will be guided by the characteristics of the early rehabilitation protocol in the ICU, structured by the rehabilitation service of Hospital Sírio-Libanês. This protocol provides recommendations for effective and applicable exercises based to the clinical reality, serving as a guiding resource in the care of critically ill patients.

Group Type ACTIVE_COMPARATOR

reabilitação fisioterapêutica tradicional

Intervention Type PROCEDURE

Active and passive exercises, and walking

physiotherapy using immersive virtual reality

The immersive virtual reality physiotherapeutic rehabilitation protocol will employ 3D virtual reality headset that simulate human sensory input to create an immersive environment.

Group Type EXPERIMENTAL

fisioterapia utilizando realidade virtual imersiva

Intervention Type PROCEDURE

Use of immersive virtual reality headset for rehabilitation sessions

Interventions

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reabilitação fisioterapêutica tradicional

Active and passive exercises, and walking

Intervention Type PROCEDURE

fisioterapia utilizando realidade virtual imersiva

Use of immersive virtual reality headset for rehabilitation sessions

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Aged ≥18 years
* Glasgow Coma Scale (GCS) score ≥14
* Richmond Agitation-Sedation Scale (RASS) score between -1 and +1
* Negative for delirium according to the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU)
* Estimated ICU stay of ≥72 hours
* Able to communicate in Portuguese
* Understand and follow verbal instructions
* Have no psychotic disorders, visual impairment or hearing loss.

Exclusion Criteria

* Hemodynamic instability
* Signs of respiratory distress
* Contact isolation for infectious diseases
* Conditions that limit head and neck movement
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospital Sirio-Libanes

OTHER

Sponsor Role lead

Responsible Party

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Wellington Yamaguti

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Wellington Yamaguti, PHD

Role: PRINCIPAL_INVESTIGATOR

Hospital Sírio-Libanês

Locations

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Hospital Sírio Libanês

São Paulo, São Paulo, Brazil

Site Status

Countries

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Brazil

Central Contacts

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Wellington Yamaguti, PHD

Role: CONTACT

1133940200 ext. 4395

Manoella C Andrade, Dra

Role: CONTACT

11950739911 ext. 4395

Facility Contacts

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Wellington Yamaguti, PHD

Role: primary

1133940200 ext. 4395

Manoella C Andrade, Dra

Role: backup

11950739911 ext. 4395

Other Identifiers

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HSL SP 2025-64

Identifier Type: -

Identifier Source: org_study_id

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