Testing Sodium Hypochlorite and Hyaluronic Acid as an Adjunct to Non-Invasive Therapy for Stage III Periodontitis Management
NCT ID: NCT07071467
Last Updated: 2025-07-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
20 participants
INTERVENTIONAL
2023-09-01
2024-01-10
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
NONE
Study Groups
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Scaling and root planing with sodium hypochlorite and hyaluronic acid
Scaling and root planing with sodium hypochlorite and hyaluronic acid
Sodium hypochlorite gel was applied first for 30 seconds, then followed by subgingival instrumentation of the site. Then, 1.8% hyaluronic acid (1.6% cross-linked, 0.2% natural hyaluronic acid ) was applied subgingivally into the periodontal pocket to seal the site.
Scaling and root planing
Scaling and root planing
Pockets were treated with sub-gingival scalling and root planning alone.
Interventions
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Scaling and root planing with sodium hypochlorite and hyaluronic acid
Sodium hypochlorite gel was applied first for 30 seconds, then followed by subgingival instrumentation of the site. Then, 1.8% hyaluronic acid (1.6% cross-linked, 0.2% natural hyaluronic acid ) was applied subgingivally into the periodontal pocket to seal the site.
Scaling and root planing
Pockets were treated with sub-gingival scalling and root planning alone.
Eligibility Criteria
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Inclusion Criteria
* CAL ≥ 5mm or bone loss affecting middle third of the root in more than two adjacent teeth.
* PPD ≥ 6mm in more than two adjacent teeth.
* Periodontal tooth loss ≤ 4 teeth.
* Systemically healthy patients.
Exclusion Criteria
* Pregnant or lactating.
* Tobacco smoker ≥ 10 cigarettes/day.
* Antibiotic treatment within previous 4 weeks.
* Acute periodontal or periapical abscess
20 Years
60 Years
ALL
No
Sponsors
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Karim Ismail
OTHER
Responsible Party
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Karim Ismail
MSc. candidate in the diagnosis, oral medicine & periodontology department
Locations
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Faculty of Dentistry, Alexandria University
Alexandria, , Egypt
Countries
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Other Identifiers
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9208891
Identifier Type: -
Identifier Source: org_study_id
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