Observational Study of the the Use of a Trigeminal Vagal Nerve Stimulator in the Routine Care of Native Americans With Diabetic Neuropathy Pain. Pain Scores, Drug Use and Glucose Measurements Will be Assessed

NCT ID: NCT07025356

Last Updated: 2025-06-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

83 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-09-23

Study Completion Date

2025-06-01

Brief Summary

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This is an observational study that will follow patients in the course of routine care and measure pain levels, glucose assessments and drug utilization for native American patients with diabetic neuropathy

Detailed Description

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Patients with diabetic neuropathy pain will have an NS100 device implanted for chronic diabetic neuropathy pain consistent with onlabel indication. All patients will be followed for 90 days post implant to measure improvements in pain, drug utilization and glucose levels.

Conditions

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Diabetic Neuropathy With Neurologic Complication

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Native Americans with Diabetic Neuropathy Pain

Use of Trigeminal Vagus cervical nerve stimulation for diabetic neuropathy pain

Implantation of a trigeminal Vagus cervical nerve stimulator system

Intervention Type DRUG

The NS 100 is a medical device used for the treatment of diabetic neuropathy pain. Routine observational monitoring will be performed

Implantation of a neurostimulator system for trigeminal vagal cervical nerve stimulation

Intervention Type DEVICE

The medium term outcomes of neurostimulation will be assessed on diabetic neuropathy pain, glucose and drug usage

Interventions

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Implantation of a trigeminal Vagus cervical nerve stimulator system

The NS 100 is a medical device used for the treatment of diabetic neuropathy pain. Routine observational monitoring will be performed

Intervention Type DRUG

Implantation of a neurostimulator system for trigeminal vagal cervical nerve stimulation

The medium term outcomes of neurostimulation will be assessed on diabetic neuropathy pain, glucose and drug usage

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Diabetic Neuropathy Pain History of failed treatment WIlling to follow blood glucose and pain scores for 90 days

Exclusion Criteria

* Bleeding diathesis Pregnancy Cardiac monitoring device Implantable Neurostimulator Inability to give informed consedn
Minimum Eligible Age

18 Years

Maximum Eligible Age

89 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Vagus Nerve Society

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Claire Marie Rangon, MD PHD

Role: STUDY_DIRECTOR

Vagus Nerve Society

Locations

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Continuum of Care Clinic

Pine Ridge, South Dakota, United States

Site Status

Countries

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United States

Other Identifiers

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VNS 001

Identifier Type: -

Identifier Source: org_study_id

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