Comparison of Effectiveness of Topical Retinoids Versus Liquid Nitrogen in Treatment of Plantar Warts(Viral Infection)

NCT ID: NCT07016360

Last Updated: 2025-06-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE4

Total Enrollment

98 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-06-15

Study Completion Date

2025-12-31

Brief Summary

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This is a comparative study between two treatment options for skin viral infection.

Detailed Description

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This is a comparative study between two treatment for viral infection in epidermal layer of skin that proliferates slowly forming thick, growths. This study will compare and evaluate the differences in efficacy between topical liquid nitrogen and topical retinoids.

Conditions

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Viral Warts

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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A

Treated with Topical adapalene gel 0.1%

Group Type EXPERIMENTAL

Topical Adapalene Gel 0.1%

Intervention Type DRUG

Topical adapalene is a retinoid that helps in epidermal changes. Cryotherapy is a liquid nitrogen applied to affected parts for 6 months

B

Treated with liquid nitrogen over affected parts

Group Type EXPERIMENTAL

Topical Liquid Nitrogen application

Intervention Type PROCEDURE

Liquid Nitrogen will be applied to affected parts.

Interventions

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Topical Adapalene Gel 0.1%

Topical adapalene is a retinoid that helps in epidermal changes. Cryotherapy is a liquid nitrogen applied to affected parts for 6 months

Intervention Type DRUG

Topical Liquid Nitrogen application

Liquid Nitrogen will be applied to affected parts.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

\-

Patients age limit 18-60 Years Patients with either gender (Male/Female) Patients with recurrent plantar warts

Exclusion Criteria

* Pregnancy/lactation. Pt on topical or systemic therapy in last 6 months. On immunosuppressants. \> 5 lesions. Pts with local secondary infections.
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Khyber Teaching Hospital

OTHER

Sponsor Role lead

Responsible Party

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Saba Naz

DOCTOR

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Saba Naz, MBBS

Role: PRINCIPAL_INVESTIGATOR

Khyber Teaching Hospital

Locations

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Khyber Teaching Hospital

Peshawar, Khyber Pakhtunkhwa, Pakistan

Site Status RECRUITING

Countries

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Pakistan

Central Contacts

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Saba Naz, MBBS

Role: CONTACT

+923209600115

Other Identifiers

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192/DME/KMC

Identifier Type: -

Identifier Source: org_study_id

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