Gamma Knife Radiosurgery on Tectal Plate Gliomas

NCT ID: NCT07015710

Last Updated: 2025-06-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-01

Study Completion Date

2024-12-01

Brief Summary

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This study aimed to assess the impact of gamma knife radiosurgery on tectal plate gliomas (TPGs).

Detailed Description

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Tectal plate gliomas (TPGs) represent a subset of brainstem gliomas that are predominantly slow-growing, low-grade tumors and rarely produce neurological deficits.

Viable options include biopsy and monitoring with serial neuroimaging, surgical resection, radiotherapy (either early following surgery or late on evidence of disease progression), chemotherapy, and stereotactic radiosurgery (SRS).

SRS using Gamma Knife radiosurgery (GKRS) has been identified in small case series as a safe and promising approach for managing TPGs that necessitate intervention beyond mere observation.

Conditions

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Gamma Knife Radiosurgery Tectal Plate Gliomas

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Tectal Plate Gliomas group

Patients underwent gamma knife radiosurgery (GKRS) for tectal plate gliomas (TPGs).

Gamma Knife Radiosurgery

Intervention Type PROCEDURE

Patients underwent gamma knife radiosurgery (GKRS) for tectal plate gliomas (TPGs).

Interventions

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Gamma Knife Radiosurgery

Patients underwent gamma knife radiosurgery (GKRS) for tectal plate gliomas (TPGs).

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age from 5 to 55 years.
* Both sexes.
* Patients underwent gamma knife radiosurgery (GKRS) for tectal plate gliomas (TPGs).

Exclusion Criteria

* High-grade glioma.
* Tumor extension beyond the tectal region.
Minimum Eligible Age

5 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Al-Azhar University

OTHER

Sponsor Role lead

Responsible Party

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Awad Mohamed Hegab

Lecturer of Neurosurgery, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Al-Azhar University (Damietta)

Damietta, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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DFM-IRB 00012367-25-05-007

Identifier Type: -

Identifier Source: org_study_id

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