Extra-cochlear Electrode Placement at the Post-auricular Vagus Nerve in Cochlear Implantation

NCT ID: NCT07011927

Last Updated: 2025-06-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-06-03

Study Completion Date

2028-07-01

Brief Summary

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This study will evaluate hearing outcomes after cochlear implantation with placement of the ECE1 ground electrode near the post-auricular vagus nerve (Arnold's nerve) to assess non-inferiority with respect to placement under the temporalis muscle.

Detailed Description

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Conditions

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Hearing Loss

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Patients scheduled for Cochlear Implantation

The experimental arm will enroll patients over the age of 18 undergoing cochlear implantation involving the placement of ECE1 at the approximate location of Arnold's nerve within the ear canal. In the proposed study, a modification to the surgical approach will be done to place ECE1 near Arnold's nerve, while still using a standard electrode array.

Group Type EXPERIMENTAL

Cochlear Implant

Intervention Type DEVICE

Eligible Cochlear Americas devices eligible for inclusion in this study include any Cochlear Americas device that has two ground electrodes.

Modified Implant Procedure

Intervention Type DEVICE

Implant procedure will be modified to place ground electrode (ECE1) near Arnold's nerve.

Interventions

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Cochlear Implant

Eligible Cochlear Americas devices eligible for inclusion in this study include any Cochlear Americas device that has two ground electrodes.

Intervention Type DEVICE

Modified Implant Procedure

Implant procedure will be modified to place ground electrode (ECE1) near Arnold's nerve.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* will be undergoing surgery for a cochlear implant from Cochlear Americas
* is willing to participate in the study

Exclusion Criteria

* has history of prior ear surgery, congenital ear malformation, or prior cochlear implantation in the ear to be implanted
* pregnant, planning to become pregnant, or breastfeeding patients cannot undergo the standard-of-care implantation procedures required for participation in the study.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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NYU Langone Health

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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J. Thomas Roland, Jr., MD

Role: PRINCIPAL_INVESTIGATOR

NYU Langone Health

Locations

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NYU Langone Health

New York, New York, United States

Site Status

Countries

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United States

Central Contacts

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Mario Svirsky

Role: CONTACT

1-212-263-7217

J. Thomas Roland, Jr., MD

Role: CONTACT

1-212-263-0460

Other Identifiers

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24-01768

Identifier Type: -

Identifier Source: org_study_id

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