DIGITALIZATION OF PERSONALISED HEALTH RISK MANAGEMENT

NCT ID: NCT06983431

Last Updated: 2025-05-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

320 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-05-05

Study Completion Date

2026-06-30

Brief Summary

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The principal objective of the project is:

* to bring together academic and business research organisations in a joint partnership integrating technological and social innovation,
* in order to develop proof-of-concept of a scalable and cost effective personalised digital health program for (pre)obesity patients,
* by integrating, in an ethical manner, adaptive AI components aimed at personalisation of the program as well as its cost management,
* with the ultimate objective to support sustained behavioural change leading to adoption and internalisation of healthy lifestyle choices.

Detailed Description

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This research project is aimed at leveraging digital tools to personalise preventive healthcare interventions for at-risk populations in ways that address the above-mentioned challenges. At risk populations, in the context of this project, generally means: Younger to middle aged (aged 30-50) sedentary individuals with (pre)obesity expressing behavioural, clinical, biochemical and anamnestic indicators of increased risk for accelerated decline of cardio-metabolic and cognitive health.

Primary outcomes will be the rate of wearable adoption/use, individualised behavioural change persistence and elicited health benefit

Secondary outcomes will include step count, activity of medium \& vigorous intensity, sleep duration/efficiency, heart rate, quality of life, body weight, body composition, blood pressure, and level of fitness as determined by the wearable or validated questionaires available on the landing page.

Participants will be randomly assigned into one of the three intervention groups and a control group. The three intervention groups:

1. Self-health coaching will be conducted using wearable and technology provided nudges allowing personalised technology-assisted real-time feedback. With this approach, on-line intervention with minimal human resource costs and high technology involvement with a potential to deliver sustainable and cost-effective behavioural change to a large at-risk population will be tested.

This intervention approx. 80 participants will be examined for the duration of 14 weeks. Long term follow up examination is envisaged, but it is beyond this study duration and will be supported by subsequent funding.
2. Health coaching (online health-coach community based) intervention will be based on applying wearable providing the most effective impact on health-related outcomes as evidenced in the exploratory study in combination with the online supervised intervention by the professional health-coach in an online group (community setting). Within this intervention the efficacy of an online supervised health coaching applied in community settings will be tested. Professional health coaching strategy using wearable-related outcomes will be provided as a golden standard of the behavioural intervention with proven efficiency. This intervention will be tested on approx. 80 participants for the duration of 14 weeks.
3. Peer coaching: Peers will be identified from the study population based on their response to specific community challenges. Natural leader characteristics will be deciphered from knowledge provided by the past supervised community-based behavioural interventions at BMC SAS and the other open sources subjected to AI driven prediction modelling. Within this intervention the efficacy of an online health coaching led by peers will be tested in an online community based setting. Peer-based health coach will lead participants through health training based on the "protocol" defining minimal coaching criteria but imposing no limits to any communication activities including the real-time access to the wearable-provided outcomes. The intervention will be tested on approx. 80 participants for the duration of 14 weeks. Long term follow up examination is envisaged, but it is beyond this study duration and will be supported by subsequent funding.
4. Control group participants will receive health coaching - related information enabling self-health coaching in a printed form during initial phenotyping visit and a wearable. The control group will consist of approx. 50 participants and observation period will be 14 weeks. Long term follow up examination is envisaged, but it is beyond this study duration and will be supported by subsequent funding.

Innovative strategies to employ AI and machine learning will be tested to support their meaningful (providing real health benefits) and cost effective use.

Conditions

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Pre-obesity Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Participants will be randomly assigned into one of the four intervention groups:

1. Self coaching (technology-assisted online intervention)
2. Health coaching - online contact with professional coach
3. Peer coaching - online contact with peer-coach
4. Control group.
Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Self coaching (technology-assisted online intervention)

Self coaching (technology-assisted online intervention)

Group Type EXPERIMENTAL

technology driven self coaching

Intervention Type BEHAVIORAL

subject will be provided with the technology driven lifestyle coaching based on the real time data from the wearables

Health coaching - online contact with professional coach

Health coaching - online contact with professional coach

Group Type EXPERIMENTAL

Health coaching

Intervention Type BEHAVIORAL

participants will be provided with the health coach (expert) driven lifestyle coaching based on the real-time data from the wearables

Peer coaching - online contact with peer-coach

Peer coaching - online contact with peer-coach

Group Type EXPERIMENTAL

Peer coaching

Intervention Type BEHAVIORAL

participants will be provided with the peer coach (expert) driven lifestyle coaching based on the real-time data from the wearables

Control group.

Wearable and basic information on healthy lifestyle will be provided, but any of the coaching strategies will be applied

Group Type ACTIVE_COMPARATOR

Active Control

Intervention Type BEHAVIORAL

participants will be provided with the wearable, but not exposed to any of the coaching strategies. Real-time data provided by the wearable will be available to them.

Interventions

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technology driven self coaching

subject will be provided with the technology driven lifestyle coaching based on the real time data from the wearables

Intervention Type BEHAVIORAL

Health coaching

participants will be provided with the health coach (expert) driven lifestyle coaching based on the real-time data from the wearables

Intervention Type BEHAVIORAL

Peer coaching

participants will be provided with the peer coach (expert) driven lifestyle coaching based on the real-time data from the wearables

Intervention Type BEHAVIORAL

Active Control

participants will be provided with the wearable, but not exposed to any of the coaching strategies. Real-time data provided by the wearable will be available to them.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* obesity (BMI 27-42 kg/m²)
* capacity and willingness to use smartphone
* capacity and willingness to use wearables
* readiness to change (validated questionaire)

Exclusion Criteria

* diseases that prevent participation in the program, or insufficiently controlled diseases, or terminal-stage illnesses
* excessive alcohol consumption or a history of other addictions
* patients currently participating in a weight-loss program (commercial, medically supervised, or a research study)
* patients using anti-obesity medications who are in the dosage adjustment phase within the last four weeks
* patients who are not mentally, physically, or technologically capable of participating
* patients who are unable to provide informed consent
* patients not adhering to the study protocol
Minimum Eligible Age

25 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital Bratislava Comenius University

UNKNOWN

Sponsor Role collaborator

Kempelen Institute of Inteligent Technologies

UNKNOWN

Sponsor Role collaborator

Slovak Academy of Sciences

OTHER_GOV

Sponsor Role lead

Responsible Party

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Jozef Ukropec

PhD, DSc

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jozef Ukropec, PhD, DSc

Role: PRINCIPAL_INVESTIGATOR

Biomedical Research Center Slovak Acad Sci

Zuzana Košutzka, A/prof., PhD

Role: STUDY_CHAIR

University Hospital Bratislava and Faculty of Medicine Comenius University

Emília Sičáková - Beblavá, Prof. Ing. PhD

Role: STUDY_DIRECTOR

University Hospital Bratislava and Faculty of Medicine Comenius University

Miroslav Beblavý, A/prof. PhD

Role: STUDY_DIRECTOR

University Hospital Bratislava and Faculty of Medicine Comenius University

Locations

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Center for Obesity Management EASO, Biomedical Research Center SAS

Bratislava, Bratislava Region, Slovakia

Site Status RECRUITING

Countries

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Slovakia

Central Contacts

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Barbara Ukropcová, Prof., MD, PhD

Role: CONTACT

00421911643630

Alex Hucovicová, Dr.

Role: CONTACT

Facility Contacts

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Barbara Ukropcova, Prof. MD, PhD

Role: primary

00421911643630

Jozef Ukropec, PhD, DSc

Role: backup

00421904059826

Other Identifiers

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09I05-03-V02-00060

Identifier Type: -

Identifier Source: org_study_id

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