Construction of Clinical Diagnostic Model for Pulmonary Hypertension
NCT ID: NCT06979011
Last Updated: 2025-05-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
199 participants
OBSERVATIONAL
2025-01-01
2025-04-30
Brief Summary
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Secondary objectives: To investigate the correlations between laboratory test indicators and echocardiographic data, and to develop new parameters based on preliminary analysis to assist in the diagnosis of pulmonary hypertension
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Detailed Description
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Collect vital signs (age, sex, etc.), clinical laboratory tests (complete blood count, biochemistry, BNP, D-dimer, and related derived parameters), and echocardiographic data from both the control group and pulmonary hypertension (PH) patients.
Obtain hemodynamic data measured via right heart catheterization (RHC) in PH patients.
Model development:
Construct a clinical diagnostic model using laboratory and echocardiographic data.
Fit hemodynamic parameters of PH patients based on their laboratory indicators, then assess the hemodynamic status using the fitted parameters and compare with actual measurements.
Secondary analyses:
Investigate correlations between echocardiographic parameters and laboratory test indicators in PH patients.
Identify core variables to develop novel diagnostic parameters and evaluate their diagnostic performance.
Conditions
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Study Design
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CASE_CONTROL
RETROSPECTIVE
Study Groups
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pulmonary hypertension
people with pulmonary hypertension
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
No gender restrictions; age \>18 years.
Availability of complete RHC records, transthoracic echocardiography (TTE), and laboratory test results (echocardiography and lab tests must be performed within one month before or after RHC).
Exclusion Criteria
Active or history of malignancy (or Malignant tumors if referring to current cases)
Hematologic disorders
ALL
Yes
Sponsors
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RenJi Hospital
OTHER
Responsible Party
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Locations
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Renji Hospital
Shanghai, Shanghai Municipality, China
Countries
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Other Identifiers
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NSFC82270050
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
LY2025-122-B
Identifier Type: -
Identifier Source: org_study_id
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