Cervical Radiculopathy Imaging Using MRN With Electrodiagnostic Correlation

NCT ID: NCT06971575

Last Updated: 2025-05-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-10-24

Study Completion Date

2026-03-31

Brief Summary

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This project will study patients with cervical radiculopathy. We will evaluate the combined diagnostic and prognostic value of magnetic resonance neurography (MRN), electrodiagnostic (EDX) studies, and historical and physical clinical elements. Specifically, this project will explore whether these data individually or in combination correlate with response to procedural and non-procedural treatment.

Detailed Description

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Conditions

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Cervical Radiculopathy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Cervical Radiculopathy Patients

Patients diagnosed with unilateral cervical radiculopathy and signs of clinical weakness.

Magnetic resonance neurography

Intervention Type DIAGNOSTIC_TEST

Patients will undergo a cervical MRI with specialized magnetic resonance neurography sequences to evaluate the extraforaminal cervical nerve roots.

Interventions

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Magnetic resonance neurography

Patients will undergo a cervical MRI with specialized magnetic resonance neurography sequences to evaluate the extraforaminal cervical nerve roots.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Patients presenting with symptoms compatible with acute or subacute unilateral (one-sided) cervical radiculopathy and signs of clinical weakness
* 18-60 years old at the time of evaluation
* Symptom onset of 2 to 12 weeks leading up to baseline visit
* Diagnosis of unilateral cervical radiculopathy, with or without spinal cord compression, based on signs and symptoms, physical exam and supported by MRI findings of radiculopathy (as evidenced by foraminal stenosis/narrowing) based on standard-of-care cervical spine MRI
* Patients who have undergone or have planned electrodiagnostic testing at HSS prior to surgery

Exclusion Criteria

* Prior cervical surgery or instrumentation
* Those who have had a prior episode of cervical radiculopathy
* History of peripheral neuropathy or another acute or chronic neurodegenerative condition
* History of stroke, cerebellar disease, or central nervous system disease
* Contraindications to undergoing a standard MRI examination (e.g., pregnancy)
* Patients presenting with bilateral cervical radiculopathy
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospital for Special Surgery, New York

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hospital for Special Surgery

New York, New York, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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J. Levi Chazen, MD

Role: CONTACT

212-774-7149

Carlo Milani, MD

Role: CONTACT

Facility Contacts

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J. Levi Chazen

Role: primary

212-774-7149

Other Identifiers

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2023-1447

Identifier Type: -

Identifier Source: org_study_id

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