The Effect of Serum Calcium Levels on Postoperative Pain: A Prospective Observational Study

NCT ID: NCT06957158

Last Updated: 2025-06-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

350 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-07-31

Study Completion Date

2025-12-31

Brief Summary

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This is a prospective observational study. To investigate the effect of serum calcium levels on postoperative pain in patients undergoing abdominal surgery, and to determine whether changes in serum calcium levels are a risk factor for postoperative pain.

Detailed Description

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This study aimed to measure the total serum calcium and ionized calcium levels both before and after surgery. Additionally, NRS scores were recorded at different time points.

Conditions

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Postoperative Pain

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Interventions

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Peripheral venous blood

Peripheral venous blood was collected before and after the surgery to measure the total serum calcium levels.

Intervention Type DIAGNOSTIC_TEST

Arterial blood

Arterial blood was collected before anesthesia induction and after removal of the artificial airway to measure ionized calcium levels.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Aged 18-70 years old
* American Society of Anesthesiologists Classification I-III
* Patients undergoing elective abdominal surgery under general anesthesia
* Patients participate voluntarily and sign an informed consent form

Exclusion Criteria

* Patients with a history of severe disease
* Patients with chronic preoperative pain and/or long-term analgesic use
* Patients with hearing disorders or verbal communication difficulties
* Patients with psychiatric disorders or cognitive dysfunction
* Patients requiring mechanical ventilation or ICU admission after surgery
* Patients with a history of substance or alcohol abuse Patients who could not cooperate with the study for any reason
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Second Affiliated Hospital of Chongqing Medical University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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The Second Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Guangyou Duan, PhD

Role: CONTACT

+86 183 2337 6014

Facility Contacts

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Guangyou Duan, PhD

Role: primary

+86 183 2337 6014

Other Identifiers

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Serum calcium levels and pain

Identifier Type: -

Identifier Source: org_study_id

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