Study to Evaluate the Performance of Navigated TKA With OrthoPilot® pheno4u TKA Level 1

NCT ID: NCT06955481

Last Updated: 2025-11-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-10-07

Study Completion Date

2028-06-30

Brief Summary

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The purpose of this PMCF study is to demonstrate the accuracy of navigation using the new pheno4uTKA Level 1 software for OrthoPilot Elite® and to evaluate its safety and performance.

Patient-related outcome measures (PROM) will be acquired to investigate functional outcome and patient satisfaction.

Detailed Description

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Conditions

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Osteoarthritis, Knee Joint Diseases Rheumatoid Arthritis of Knee Posttraumatic Arthropathy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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pheno4u TKA Level 1

Navigation of TKA (Total Knee Arthroplasty) using the new pheno4uTKA Level 1 software for OrthoPilot Elite®.

Navigated Total Knee Arthroplasty

Intervention Type PROCEDURE

The OrthoPilot® Software Pheno4u TKA Level 1 is an application software for computer aided navigation of surgical instruments and serves (in combination with compatible hardware and compatible navigated instruments) as an optional aid for the surgeon during the preparation of the implant site for a compatible knee endoprosthesis.

Interventions

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Navigated Total Knee Arthroplasty

The OrthoPilot® Software Pheno4u TKA Level 1 is an application software for computer aided navigation of surgical instruments and serves (in combination with compatible hardware and compatible navigated instruments) as an optional aid for the surgeon during the preparation of the implant site for a compatible knee endoprosthesis.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Indication for a TKA with the OrthoPilot® Navigation System with a Aesculap total knee endo-prosthesis
* Written signed informed consent of patient
* Willingness and mental ability to participate at the long-term follow-up examinations

Exclusion Criteria

* Pregnancy
* Patients \< 18 years or \> 80 years
* Patients unable to participate at the follow-up examination (physically, mentally)
* Previous joint replacement at the index knee
* ASA classification \> 3 ( ASA I: A healthy patient without systemic diseases. ASA II: A patient with a mild systemic disease that is well controlled (e.g., well-controlled diabetes or hypertension). ASA III: A patient with a severe systemic disease that causes functional limitations (e.g., poorly controlled diabetes, COPD). ASA IV: A patient with a life-threatening systemic disease (e.g., severe heart failure, sepsis). ASA V: A dying patient who is not expected to survive without the operation. ASA VI: A deceased patient whose organs are being removed for donation.)
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Raylytic GmbH

INDUSTRY

Sponsor Role collaborator

Aesculap AG

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jörg Lützner, Prof. Dr.

Role: PRINCIPAL_INVESTIGATOR

Universitätsklinikum Carl Gustav Carus

Locations

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Šumperk Hospital Inc.

Šumperk, , Czechia

Site Status NOT_YET_RECRUITING

Klinikum Konstanz GmbH

Konstanz, Baden-Wurttemberg, Germany

Site Status NOT_YET_RECRUITING

Park-Klinik Weißensee

Berlin, , Germany

Site Status RECRUITING

Universitätsklinikum Carl Gustav Carus

Dresden, , Germany

Site Status NOT_YET_RECRUITING

Countries

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Czechia Germany

Central Contacts

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Heike Oberascher

Role: CONTACT

+49 7461 95 ext. 0

Stefan Maenz, Dr.

Role: CONTACT

+49 7461 95 ext. 0

Facility Contacts

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Ján Debre, Dr.med

Role: primary

Role: backup

+420 583 333 ext. 0

Gunnar Ochs, Prof.Dr.med

Role: primary

+49 7531 801 ext. 0

Oliver Hauschild, Prof.Dr.med

Role: primary

+49 7531 801 ext. 0

Jörg Lützner, Prof. Dr.

Role: primary

+49 351 458 150 ext. 0

Other Identifiers

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AAG-O-H-25084

Identifier Type: -

Identifier Source: org_study_id

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