Effectiveness of Combined Neural Mobilization With Manual Myofascial Release for Sciatic Pain Relief

NCT ID: NCT06947785

Last Updated: 2025-04-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-04-15

Study Completion Date

2026-01-31

Brief Summary

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This study will address to evaluate and compare both Neural mobilization and Manual Myofascial Release of piriformis and Lumbar muscles in sciatic pain with the aim of evaluating and identifying the most effective intervention for managing this specific condition, and provide valuable insights into the effectiveness, mechanisms, and practical considerations associated with these interventions, ultimately contributing to evidence based and patient centered care.

Detailed Description

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MFR is a hands-on technique targeting fascial restrictions that may contribute to pain and reduced mobility. Barnes proposed that releasing fascial adhesions can improve circulation, reduce nerve compression, and enhance tissue flexibility. In a study by Ajimsha et al. , MFR was found to significantly reduce pain and improve physical function in patients with nonspecific low back pain. There is a lack of comparative research assessing the relative efficacy of neural mobilization andMFR in sciatic pain management. While both techniques are rooted in distinct mechanisms neural desensitization versus fascial release they may have overlapping benefits in improving mobility and reducing pain. This study addresses this research gap by directly comparing the two approaches in individuals with sciatic pain.

Conditions

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Sciatica

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Combined Neural Mobilization with Manual myofascial Release

Combined neural mobilization of Sciatic nerve and manual myofascial release of piriformis and back muscles will be given to this group.

Group Type EXPERIMENTAL

Combined Neural Mobilization with Manual myofascial Release

Intervention Type OTHER

Combined neural mobilization with manual myofascial release will be provided to each subject.

Neural Mobilization

Only neural mobilization of Sciatic nerve will be given to this group.

Group Type ACTIVE_COMPARATOR

Neural Mobilization

Intervention Type OTHER

neural mobilization will be provided to each subject.

Manual Myofascial Release

Only manual myofascial release of piriformis and back muscles will be given to this group.

Group Type ACTIVE_COMPARATOR

Manual Myofascial Release

Intervention Type OTHER

Manual myofascial release will be provided to each subject.

Interventions

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Combined Neural Mobilization with Manual myofascial Release

Combined neural mobilization with manual myofascial release will be provided to each subject.

Intervention Type OTHER

Neural Mobilization

neural mobilization will be provided to each subject.

Intervention Type OTHER

Manual Myofascial Release

Manual myofascial release will be provided to each subject.

Intervention Type OTHER

Other Intervention Names

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Neural Mobilization Manual Myofascial Release Combined Neural Mobilization with Manual myofascial Release Manual Myofascial Release Combined Neural Mobilization with Manual myofascial Release Neural Mobilization

Eligibility Criteria

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Inclusion Criteria

1. Clinically diagnosed unilateral sciatic pain for \>3 months.
2. Positive Straight Leg Raise (SLR).

Exclusion Criteria

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1. Recent spinal surgery or trauma.
2. Neurological deficits or systemic conditions affecting the nervous system.
3. Any other red flags
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Riphah International University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Amnah Anum, MSPT

Role: PRINCIPAL_INVESTIGATOR

Riphah International University

Locations

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Riphah International University, Malakand

Chakdara, KPK, Pakistan

Site Status

Countries

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Pakistan

Central Contacts

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Amnah Anum, MSPT

Role: CONTACT

0332-4896605

Facility Contacts

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Amnah Anum, MSPT

Role: primary

03324896605

Other Identifiers

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REC-01004 Anwar Ullah

Identifier Type: -

Identifier Source: org_study_id

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