Screening of Lactose Intolerance Among IBS Patients Diarrhea Dominant

NCT ID: NCT06931379

Last Updated: 2026-01-06

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 70 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2026-01-31
• Study Completion Date: 2027-02-28

Brief Summary

This cross-sectional study aims to determine the prevalence of lactose intolerance among patients with chronic diarrhea, assess its correlation with age and gender, and evaluate common symptoms in affected patients. The study will collect demographic data, conduct lactose intolerance testing via PCR, and use a symptom questionnaire.

Detailed Description

The study is designed as a cross-sectional analysis conducted at a single healthcare center. Its primary objectives are:

To determine the point prevalence of lactose intolerance in patients suffering from chronic diarrhea (lasting more than four weeks).

To explore potential correlations between lactose intolerance and demographic factors such as age and gender.

To identify the most common symptoms associated with lactose intolerance in this patient population.

Methodology:

Data Collection: Demographic information (age, sex, medical history, and diarrhea duration) will be gathered.

Lactose Intolerance Testing: Polymerase Chain Reaction (PCR) will be employed to diagnose lactose intolerance.

Symptom Questionnaire: A standardized questionnaire will be administered to document symptoms like abdominal pain, bloating, flatulence, diarrhea, and nausea.

Conditions

Lactose Intolerance

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

adult patients aged 18-70 years diagnosed as IBS diarrhea dominant

The target population comprises individuals who meet the following inclusion criteria:

Adults aged between 18 and 70 years.

Diagnosed with IBS diarrhea dominant

Both males and females are eligible for participation.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• All Patients with IBS diarrhea dominant type meet Rome criteria attending at Al-Rajhy University Hospital during 6 months (from march to September). A patient must have recurrent abdominal pain (at least 1 day per week in the last 3 months) associated with at least two of the following:

1. Related to defecation (pain improves or worsens with bowel movements).

2. Change in stool frequency (diarrhea or constipation).

3. Change in stool form (appearance) (loose, watery, hard, or lumpy).

• Patients aged >18 years.
• Both males and females

Exclusion Criteria

• -patient aged<18 years old.
• Patients with chronic diarrhea don't meet Rome criteria
• patients with malignancies

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 70 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Christina Shahat Ayoub

resident at the tropical medicine department

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

Screening of lactose intolera

Identifier Type: -

Identifier Source: org_study_id