The Investigation of Predicting Mortality and Morbidity in Patients Admitted to Intensive Care Unit With Thoracic Trauma Using Selected Biomarkers and Parameters

NCT ID: NCT06930222

Last Updated: 2025-04-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-04-15

Study Completion Date

2024-04-15

Brief Summary

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This prospective study aimed to predict morbidity and mortality after thoracic trauma in intensive care unit evaluated clinical and biochemical data of 50 intensive care unit patients. The research examined demographic factors such as gender, age, and smoking status, trauma scoring systems like ISS and RTS as well as biomarkers such as Surfactant-d and oxygenation parameters including the ROX index, PaO₂/FiO₂ ratio and FiO₂.

Detailed Description

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Conditions

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Thorax Traumas

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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thorax trauma patients

thorax trauma patients admitted to icu

blood sampling

Intervention Type DIAGNOSTIC_TEST

blood samples obtained for 3 different days, limited to 5cc

Interventions

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blood sampling

blood samples obtained for 3 different days, limited to 5cc

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Patients with thoracic trauma between the ages of 18-85
* Patients who have been monitored in intensive care for at least 1 week

Exclusion Criteria

* Being outside the age range of 18-85
* Pregnant patients
* Patients whose intensive care follow-up lasted less than 1 week
* Patients who do not want to be included in the study
* Patients with a lung malignancy diagnosis before admission
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Suleyman Demirel University

OTHER

Sponsor Role lead

Responsible Party

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Suleyman Sencer CELİK

RESEARCH ASSISTANT

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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pınar karabacak

Role: STUDY_DIRECTOR

Suleyman Demirel University

Locations

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Suleyman Demirel University

Isparta, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Determann RM, Royakkers AA, Haitsma JJ, Zhang H, Slutsky AS, Ranieri VM, Schultz MJ. Plasma levels of surfactant protein D and KL-6 for evaluation of lung injury in critically ill mechanically ventilated patients. BMC Pulm Med. 2010 Feb 16;10:6. doi: 10.1186/1471-2466-10-6.

Reference Type BACKGROUND
PMID: 20158912 (View on PubMed)

Baker JE, Millar DA, Heh V, Goodman MD, Pritts TA, Janowak CF. Does chest wall Organ Injury Scale (OIS) or Abbreviated Injury Scale (AIS) predict outcomes? An analysis of 16,000 consecutive rib fractures. Surgery. 2020 Jul;168(1):198-204. doi: 10.1016/j.surg.2020.04.032. Epub 2020 May 13.

Reference Type BACKGROUND
PMID: 32507628 (View on PubMed)

Lundin A, Akram SK, Berg L, Goransson KE, Enocson A. Thoracic injuries in trauma patients: epidemiology and its influence on mortality. Scand J Trauma Resusc Emerg Med. 2022 Dec 12;30(1):69. doi: 10.1186/s13049-022-01058-6.

Reference Type BACKGROUND
PMID: 36503613 (View on PubMed)

Other Identifiers

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SENCER-CELIK-001

Identifier Type: -

Identifier Source: org_study_id

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