Renal Perfusion and the Development of AKI Following Traumatic Injury
NCT ID: NCT06917053
Last Updated: 2025-04-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
20 participants
OBSERVATIONAL
2024-04-13
2026-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Traumatic haemorrhagic shock
Ultrasound (including contrast enhanced ultrasound)
Ultrasound measures: contrast enhanced ultrasound (CEUS) of the kidney, venous excess ultrasound (VExUS), echocardiography
Sublingual incident dark field videomicroscopy
Sublingual incident dark field (IDF) videomicroscopy
Urinary oxygen tension.
Continuous urinary oxygen tension
Interventions
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Ultrasound (including contrast enhanced ultrasound)
Ultrasound measures: contrast enhanced ultrasound (CEUS) of the kidney, venous excess ultrasound (VExUS), echocardiography
Sublingual incident dark field videomicroscopy
Sublingual incident dark field (IDF) videomicroscopy
Urinary oxygen tension.
Continuous urinary oxygen tension
Eligibility Criteria
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Inclusion Criteria
* Within 24 hours of ICU admission following traumatic injury
* Received any blood products during initial resuscitation
* Lactate \> 2 mmol/l at any stage prior to study enrolment
Exclusion Criteria
* Patients with un-survivable injuries / not expected to survive 24 hours in whom the intent of treatment is palliative
* Known CKD 4 or end stage renal failure
* Pregnancy
18 Years
ALL
No
Sponsors
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King's College Hospital NHS Trust
OTHER
Responsible Party
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Locations
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King's College Hospital
London, , United Kingdom
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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334289
Identifier Type: -
Identifier Source: org_study_id
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