The Prognostic Value of PET/CT for Tumor Progression in Patients With Metastatic Hormone-sensitive Prostate Cancer

NCT ID: NCT06915714

Last Updated: 2025-04-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

45 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-06-02

Study Completion Date

2025-02-28

Brief Summary

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Investigators retrospectively collected data from consecutive patients treated at the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, from October 2020 to March 2024. The inclusion criteria were as follows: (1) patients with diagnosis of metastatic hormone-sensitive prostate cancer, confirmed by PSA levels, radiographic tests and pathological information; (2) patients who underwent FDG and PSMA PET/CT prior to the initiation of medical treatment. The exclusion criteria were as follows: (1) patients who received novel hormone therapy or a prostate biopsy prior to PET/CT; (2) patients with other malignancies; (3) patients received hormone therapy without NHT; (4) patients received chemotherapy or radiotherapy prior to or during novel hormone therapy; (5) absence of follow-up data at the hospital.

Detailed Description

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Conditions

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Prostate Cancer Metastatic Disease PET / CT

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Group1

PCa40%MTV-P = High, PCa40%MTV-G = Low

No interventions assigned to this group

Group2

PCa40%MTV-P = Low, PCa40%MTV-G = High

No interventions assigned to this group

Group3

PCa40%MTV-P = Low, PCa40%MTV-G = Low

No interventions assigned to this group

Group4

PCa40%MTV-P = High, PCa40%MTV-G = High

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* patients with diagnosis of metastatic hormone-sensitive prostate cancer, confirmed by PSA levels, radiographic tests and pathological information
* patients who underwent FDG and PSMA PET/CT prior to the initiation of medical treatment

Exclusion Criteria

* patients who received novel hormone therapy or a prostate biopsy prior to PET/CT
* patients with other malignancies
* patients received hormone therapy without novel hormone therapy
* patients received chemotherapy or radiotherapy prior to or during novel hormone therapy
* absence of follow-up data at our institution
Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Sun Yat-sen University

OTHER

Sponsor Role lead

Responsible Party

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Zheng fufu

Professor, Phd, Md

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Fangzheng Xiang

Role: PRINCIPAL_INVESTIGATOR

First affiliated hospital, Sun Yat-sen univeristy

Locations

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First affiliated hospital, Sun Yat-sen univeristy

Guangzhou, Guangdong, China

Site Status

Countries

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China

Other Identifiers

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IIT-2025-117

Identifier Type: -

Identifier Source: org_study_id

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